The Emergence of Microphysiological Systems (Organs-on-chips) as Paradigm-changing Tools for Toxicologic Pathology.
Toxicol Pathol
; 47(1): 4-10, 2019 01.
Article
em En
| MEDLINE
| ID: mdl-30407146
ABSTRACT
Microphysiological systems (MPS), commonly known as organs-on-chips, are a rapidly advancing technology that promises to impact many areas of medical and toxicological pathology. In this minireview, the history of MPS and its potential utility in safety assessment are described with the toxicologic pathologist in mind. Several MPS development focus areas are defined, and recent progress in the area is highlighted. MPS will likely become an important tool for the toxicologic pathologist as part of our role in the safety assessment process within the pharmaceutical, biotechnology, medical device, and cosmetic and agrichemical industries.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Patologia
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Toxicologia
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Microfluídica
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Procedimentos Analíticos em Microchip
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Dispositivos Lab-On-A-Chip
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article