Microwave-assisted synthesis of biologically relevant steroidal 17-<i>exo</i>-pyrazol-5'-ones from a norpregnene precursor by a side-chain elongation/heterocyclization sequence.

Mótyán, Gergo; Mérai, László; Kiss, Márton Attila; Schelz, Zsuzsanna; Sinka, Izabella; Zupkó, István; Frank, Éva

Microwave-assisted synthesis of biologically relevant steroidal 17-exo-pyrazol-5'-ones from a norpregnene precursor by a side-chain elongation/heterocyclization sequence.

Mótyán, Gergo; Mérai, László; Kiss, Márton Attila; Schelz, Zsuzsanna; Sinka, Izabella; Zupkó, István; Frank, Éva.

Afiliação

Mótyán G; Department of Organic Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary.
Mérai L; Department of Organic Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary.
Kiss MA; Department of Organic Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary.
Schelz Z; Department of Pharmacodynamics and Biopharmacy, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.
Sinka I; Department of Pharmacodynamics and Biopharmacy, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.
Zupkó I; Department of Pharmacodynamics and Biopharmacy, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.
Frank É; Department of Organic Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary.

Beilstein J Org Chem ; 14: 2589-2596, 2018.

Article em En | MEDLINE | ID: mdl-30410620