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Prediction of Human Distribution Volumes of Compounds in Various Elimination Phases Using Physiologically Based Pharmacokinetic Modeling and Experimental Pharmacokinetics in Animals.
Shimizu, Hidetoshi; Yoshida, Kosuke; Nakada, Tomohisa; Kojima, Koki; Ogasawara, Akihito; Nakamaru, Yoshinobu; Yamazaki, Hiroshi.
Afiliação
  • Shimizu H; Mitsubishi Tanabe Pharma Corporation, Toda, Saitama, Japan (H.S., K.Y., T.N., K.K., A.O., Y.N.); and Showa Pharmaceutical University, Machida, Tokyo, Japan (H.Y.) shimizu.hidetoshi@ma.mt-pharma.co.jp hyamazak@ac.shoyaku.ac.jp.
  • Yoshida K; Mitsubishi Tanabe Pharma Corporation, Toda, Saitama, Japan (H.S., K.Y., T.N., K.K., A.O., Y.N.); and Showa Pharmaceutical University, Machida, Tokyo, Japan (H.Y.).
  • Nakada T; Mitsubishi Tanabe Pharma Corporation, Toda, Saitama, Japan (H.S., K.Y., T.N., K.K., A.O., Y.N.); and Showa Pharmaceutical University, Machida, Tokyo, Japan (H.Y.).
  • Kojima K; Mitsubishi Tanabe Pharma Corporation, Toda, Saitama, Japan (H.S., K.Y., T.N., K.K., A.O., Y.N.); and Showa Pharmaceutical University, Machida, Tokyo, Japan (H.Y.).
  • Ogasawara A; Mitsubishi Tanabe Pharma Corporation, Toda, Saitama, Japan (H.S., K.Y., T.N., K.K., A.O., Y.N.); and Showa Pharmaceutical University, Machida, Tokyo, Japan (H.Y.).
  • Nakamaru Y; Mitsubishi Tanabe Pharma Corporation, Toda, Saitama, Japan (H.S., K.Y., T.N., K.K., A.O., Y.N.); and Showa Pharmaceutical University, Machida, Tokyo, Japan (H.Y.).
  • Yamazaki H; Mitsubishi Tanabe Pharma Corporation, Toda, Saitama, Japan (H.S., K.Y., T.N., K.K., A.O., Y.N.); and Showa Pharmaceutical University, Machida, Tokyo, Japan (H.Y.) shimizu.hidetoshi@ma.mt-pharma.co.jp hyamazak@ac.shoyaku.ac.jp.
Drug Metab Dispos ; 47(2): 114-123, 2019 02.
Article em En | MEDLINE | ID: mdl-30420404
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Farmacocinética / Pesquisa Farmacêutica / Modelos Biológicos Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Farmacocinética / Pesquisa Farmacêutica / Modelos Biológicos Idioma: En Ano de publicação: 2019 Tipo de documento: Article