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Preventing Lck Activation in CAR T Cells Confers Treg Resistance but Requires 4-1BB Signaling for Them to Persist and Treat Solid Tumors in Nonlymphodepleted Hosts.
Suryadevara, Carter M; Desai, Rupen; Farber, S Harrison; Choi, Bryan D; Swartz, Adam M; Shen, Steven H; Gedeon, Patrick C; Snyder, David J; Herndon, James E; Healy, Patrick; Reap, Elizabeth A; Archer, Gary E; Fecci, Peter E; Sampson, John H; Sanchez-Perez, Luis.
Afiliação
  • Suryadevara CM; Department of Neurosurgery, Duke Brain Tumor Immunotherapy Program, Duke University Medical Center, Durham, North Carolina.
  • Desai R; The Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina.
  • Farber SH; Department of Pathology, Duke University Medical Center, Durham, North Carolina.
  • Choi BD; Department of Neurosurgery, Duke Brain Tumor Immunotherapy Program, Duke University Medical Center, Durham, North Carolina.
  • Swartz AM; The Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina.
  • Shen SH; Department of Neurosurgery, Duke Brain Tumor Immunotherapy Program, Duke University Medical Center, Durham, North Carolina.
  • Gedeon PC; The Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina.
  • Snyder DJ; Department of Neurosurgery, Duke Brain Tumor Immunotherapy Program, Duke University Medical Center, Durham, North Carolina.
  • Herndon JE; The Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina.
  • Healy P; Department of Pathology, Duke University Medical Center, Durham, North Carolina.
  • Reap EA; Department of Neurosurgery, Duke Brain Tumor Immunotherapy Program, Duke University Medical Center, Durham, North Carolina.
  • Archer GE; The Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina.
  • Fecci PE; Department of Pathology, Duke University Medical Center, Durham, North Carolina.
  • Sampson JH; Department of Neurosurgery, Duke Brain Tumor Immunotherapy Program, Duke University Medical Center, Durham, North Carolina.
  • Sanchez-Perez L; The Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina.
Clin Cancer Res ; 25(1): 358-368, 2019 01 01.
Article em En | MEDLINE | ID: mdl-30425092
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antígenos CD28 / Membro 9 da Superfamília de Receptores de Fatores de Necrose Tumoral / Receptores de Antígenos Quiméricos / Neoplasias Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antígenos CD28 / Membro 9 da Superfamília de Receptores de Fatores de Necrose Tumoral / Receptores de Antígenos Quiméricos / Neoplasias Idioma: En Ano de publicação: 2019 Tipo de documento: Article