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Novel hybrid molecule overcomes the limited response of solid tumours to HDAC inhibitors via suppressing JAK1-STAT3-BCL2 signalling.
Huang, Zhi; Zhou, Wei; Li, Yongtao; Cao, Mei; Wang, Tianqi; Ma, Yakun; Guo, Qingxiang; Wang, Xin; Zhang, Chao; Zhang, Chenglan; Shen, Wenzhi; Liu, Yanhua; Chen, Yanan; Zheng, Jianyu; Yang, Shengyong; Fan, Yan; Xiang, Rong.
Afiliação
  • Huang Z; Department of Medicinal Chemistry, School of Medicine, Nankai University, Tianjin 300071, China.
  • Zhou W; Department of Medicinal Chemistry, School of Medicine, Nankai University, Tianjin 300071, China.
  • Li Y; Department of Medicinal Chemistry, School of Medicine, Nankai University, Tianjin 300071, China.
  • Cao M; Department of Medicinal Chemistry, School of Medicine, Nankai University, Tianjin 300071, China.
  • Wang T; Department of Medicinal Chemistry, School of Medicine, Nankai University, Tianjin 300071, China.
  • Ma Y; Department of Medicinal Chemistry, School of Medicine, Nankai University, Tianjin 300071, China.
  • Guo Q; Department of Medicinal Chemistry, School of Medicine, Nankai University, Tianjin 300071, China.
  • Wang X; Department of Medicinal Chemistry, School of Medicine, Nankai University, Tianjin 300071, China.
  • Zhang C; Department of Medicinal Chemistry, School of Medicine, Nankai University, Tianjin 300071, China.
  • Zhang C; Department of Medicinal Chemistry, School of Medicine, Nankai University, Tianjin 300071, China.
  • Shen W; Department of Pathology and Institute of Precision Medicine, Jining Medical University, Jining 272067, China.
  • Liu Y; State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.
  • Chen Y; State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.
  • Zheng J; State Key Laboratory and Institute of Elemento-Organic Chemistry, Collaborative Innovation Center of Chemical Science and Engineering, Nankai University, Tianjin 300071, China.
  • Yang S; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Collaborative Innovation Center for Biotherapy and Sichuan University, Chengdu 610041, China.
  • Fan Y; Department of Medicinal Chemistry, School of Medicine, Nankai University, Tianjin 300071, China.
  • Xiang R; State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.
Theranostics ; 8(18): 4995-5011, 2018.
Article em En | MEDLINE | ID: mdl-30429882
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Neoplasias da Mama / Transdução de Sinais / Inibidores de Histona Desacetilases / Antineoplásicos Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Neoplasias da Mama / Transdução de Sinais / Inibidores de Histona Desacetilases / Antineoplásicos Idioma: En Ano de publicação: 2018 Tipo de documento: Article