Circular RNA CCDC66 targets DCX to regulate cell proliferation and migration by sponging miR-488-3p in Hirschsprung's disease.

Wen, Zechao; Shen, Qiyang; Zhang, Hua; Su, Yang; Zhu, Zhongxian; Chen, Guanglin; Peng, Lei; Li, Hongxing; Du, Chunxia; Xie, Hua; Xu, Xiaoqun; Tang, Weibing

Wen, Zechao; Shen, Qiyang; Zhang, Hua; Su, Yang; Zhu, Zhongxian; Chen, Guanglin; Peng, Lei; Li, Hongxing; Du, Chunxia; Xie, Hua; Xu, Xiaoqun; Tang, Weibing.

Afiliação

Wen Z; Department of Pediatric Surgery, Children's Hospital of Nanjing Medical University, Nanjing, China.
Shen Q; State Key Laboratory of Reproductive Medicine, Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China.
Zhang H; Department of Pediatric Surgery, Children's Hospital of Nanjing Medical University, Nanjing, China.
Su Y; State Key Laboratory of Reproductive Medicine, Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China.
Zhu Z; Department of Pediatric Surgery, Children's Hospital of Nanjing Medical University, Nanjing, China.
Chen G; State Key Laboratory of Reproductive Medicine, Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China.
Peng L; Department of Pediatric Surgery, Children's Hospital of Nanjing Medical University, Nanjing, China.
Li H; State Key Laboratory of Reproductive Medicine, Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China.
Du C; Department of Pediatric Surgery, Children's Hospital of Nanjing Medical University, Nanjing, China.
Xie H; State Key Laboratory of Reproductive Medicine, Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China.
Xu X; Department of Pediatric Surgery, Children's Hospital of Nanjing Medical University, Nanjing, China.
Tang W; State Key Laboratory of Reproductive Medicine, Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China.

J Cell Physiol ; 234(7): 10576-10587, 2019 07.

Article em En | MEDLINE | ID: mdl-30443988

Assuntos

Proteínas do Olho/genética; Doença de Hirschsprung/genética; MicroRNAs/genética; Proteínas Associadas aos Microtúbulos/genética; Neuropeptídeos/genética; RNA Circular/genética; Movimento Celular/genética; Proliferação de Células/genética; Proteínas do Domínio Duplacortina; Proteína Duplacortina; Feminino; Regulação da Expressão Gênica/genética; Células HEK293; Doença de Hirschsprung/patologia; Humanos; Lactente; Masculino; Proteínas de Ligação a RNA/genética

Palavras-chave

Hirschsprung's disease; circular RNA; competing endogenous RNAs; neuronal development

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neuropeptídeos / MicroRNAs / Proteínas do Olho / RNA Circular / Doença de Hirschsprung / Proteínas Associadas aos Microtúbulos Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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