Knock-in of the <i>Wt1</i> R394W mutation causes MDS and cooperates with <i>Flt3/ITD</i> to drive aggressive myeloid neoplasms in mice.

Knock-in of the Wt1 R394W mutation causes MDS and cooperates with Flt3/ITD to drive aggressive myeloid neoplasms in mice.

Annesley, Colleen E; Rabik, Cara; Duffield, Amy S; Rau, Rachel E; Magoon, Daniel; Li, Li; Huff, Vicki; Small, Donald; Loeb, David M; Brown, Patrick.

Afiliação

Annesley CE; Department of Pediatrics, University of Washington, Seattle, WA, USA.
Rabik C; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Duffield AS; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Rau RE; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Magoon D; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Li L; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Huff V; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Small D; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Loeb DM; Department of Molecular Genetics/Cancer Genetics, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.
Brown P; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, Baltimore, MD, USA.