Composition, structure and function of the eukaryotic flagellum distal tip.
Essays Biochem
; 62(6): 815-828, 2018 12 07.
Article
em En
| MEDLINE
| ID: mdl-30464008
ABSTRACT
Cilia and flagella are long extensions commonly found on the surface of eukaryotic cells. In fact, most human cells have a flagellum, and failure to correctly form cilia leads to a spectrum of diseases gathered under the name 'ciliopathies'. The cilium distal tip is where it grows and signals. Yet, out of the flagellar regions, the distal tip is probably the least intensively studied. In this review, we will summarise the current knowledge on the diverse flagellar tip structures, the dynamicity and signalling that occurs here and the proteins localising to this important cellular region.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Cílios
/
Flagelos
/
Microtúbulos
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article