CCL22-Producing Resident Macrophages Enhance T Cell Response in Sjögren's Syndrome.

Ushio, Aya; Arakaki, Rieko; Otsuka, Kunihiro; Yamada, Akiko; Tsunematsu, Takaaki; Kudo, Yasusei; Aota, Keiko; Azuma, Masayuki; Ishimaru, Naozumi

Ushio, Aya; Arakaki, Rieko; Otsuka, Kunihiro; Yamada, Akiko; Tsunematsu, Takaaki; Kudo, Yasusei; Aota, Keiko; Azuma, Masayuki; Ishimaru, Naozumi.

Afiliação

Ushio A; Department of Oral Molecular Pathology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Arakaki R; Department of Oral Molecular Pathology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Otsuka K; Department of Oral Molecular Pathology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Yamada A; Department of Oral Molecular Pathology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Tsunematsu T; Department of Pathology and Laboratory Medicine, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Kudo Y; Department of Oral Molecular Pathology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Aota K; Department of Oral Medicine, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Azuma M; Department of Oral Medicine, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Ishimaru N; Department of Oral Molecular Pathology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.

Front Immunol ; 9: 2594, 2018.

Article em En | MEDLINE | ID: mdl-30467506

Assuntos

Quimiocina CCL22/metabolismo; Aparelho Lacrimal/patologia; Macrófagos/imunologia; Glândulas Salivares/patologia; Síndrome de Sjogren/imunologia; Linfócitos T/imunologia; Animais; Anticorpos Monoclonais/administração & dosagem; Autoimunidade; Células Cultivadas; Quimiocina CCL22/imunologia; Modelos Animais de Doenças; Feminino; Humanos; Ativação Linfocitária; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Mutantes; Timectomia

Palavras-chave

Sjögren's syndrome; T cell response; autoimmunity; chemokine; salivary gland; tissue-resident macrophage

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glândulas Salivares / Linfócitos T / Síndrome de Sjogren / Quimiocina CCL22 / Aparelho Lacrimal / Macrófagos Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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