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IMB-T130 targets 3-dehydroquinate synthase and inhibits Mycobacterium tuberculosis.
Zhu, Ningyu; Wang, Xia; Li, Dongsheng; Lin, Yuan; You, Xuefu; Jiang, Jiandong; Xu, Yanni; Jiang, Wei; Si, Shuyi.
Afiliação
  • Zhu N; Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100050, China.
  • Wang X; Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100050, China.
  • Li D; Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100050, China.
  • Lin Y; State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
  • You X; Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100050, China.
  • Jiang J; Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100050, China.
  • Xu Y; State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
  • Jiang W; Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100050, China.
  • Si S; Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100050, China.
Sci Rep ; 8(1): 17439, 2018 11 28.
Article em En | MEDLINE | ID: mdl-30487577
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fósforo-Oxigênio Liases / Inibidores Enzimáticos / Mycobacterium tuberculosis / Antituberculosos Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fósforo-Oxigênio Liases / Inibidores Enzimáticos / Mycobacterium tuberculosis / Antituberculosos Idioma: En Ano de publicação: 2018 Tipo de documento: Article