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Modification of the Myelotoxic and Antitumor Effects of Polychemotherapy by Polysaccharides from Tussilago farfara L.
Safonova, E A; Lopatina, K A; Razina, T G; Zueva, E P; Fedorova, E P; Gur'ev, A M; Belousov, M V.
Afiliação
  • Safonova EA; E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia. safonova_7@mail.ru.
  • Lopatina KA; E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia.
  • Razina TG; E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia.
  • Zueva EP; E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia.
  • Fedorova EP; E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia.
  • Gur'ev AM; Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia.
  • Belousov MV; Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia.
Bull Exp Biol Med ; 166(2): 197-200, 2018 Dec.
Article em En | MEDLINE | ID: mdl-30488221
ABSTRACT
The experiments on C57Bl/6 mice with Lewis lung carcinoma showed that addition of Tussilago farfara L. polysaccharides to conventional cisplatin/paclitaxel polychemotherapy moderated neutropenia caused by antitumor therapy and increased its efficiency. The stimulating effect of polysaccharides on the granulopoietic lineage cells is comparable with that of recombinant CSF Neupogen.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polissacarídeos / Protocolos de Quimioterapia Combinada Antineoplásica / Cisplatino / Paclitaxel / Carcinoma Pulmonar de Lewis / Tussilago / Antineoplásicos Fitogênicos Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polissacarídeos / Protocolos de Quimioterapia Combinada Antineoplásica / Cisplatino / Paclitaxel / Carcinoma Pulmonar de Lewis / Tussilago / Antineoplásicos Fitogênicos Idioma: En Ano de publicação: 2018 Tipo de documento: Article