Influence of dietary restriction and low-intensity exercise on weight loss and insulin sensitivity in obese equids.
J Vet Intern Med
; 33(1): 280-286, 2019 Jan.
Article
em En
| MEDLINE
| ID: mdl-30520164
ABSTRACT
BACKGROUND:
The importance of including exercise with dietary modification for the management of obese equids is not clearly understood.OBJECTIVES:
To evaluate the effect of a practical low-intensity exercise regimen, in addition to dietary restriction, on indices of insulin sensitivity (SI) and plasma adipokine concentrations in obese equids. ANIMALS Twenty-four obese (body condition score [BCS] ≥ 7/9) horses and ponies.METHODS:
Over a 12-week period, animals received either dietary restriction only (DIET) or dietary restriction plus low-intensity exercise (DIET+EX). All animals were provided with a restricted ration of grass hay at 1.25% body weight (BW) on a dry matter basis, providing 82.5% estimated digestible energy requirements. The DIET+EX group undertook low-intensity exercise 5 days per week on an automated horse walker. Before and after weight loss, total body fat mass (TBFM) was determined, indices of SI were calculated using minimal model analysis of a frequently sampled IV glucose tolerance test, and adipokines plus inflammatory biomarkers were measured using validated assays.RESULTS:
Decreases in BCS, BW, and TBFM were similar between groups (all P > .05). After weight loss, animals in both groups had decreased basal insulin and leptin concentrations, and increased adiponectin concentrations (all P < .001). Furthermore, animals in the DIET+EX group had significantly improved SI and decreased serum amyloid A concentrations relative to animals in the DIET group (both P = .01). CONCLUSIONS AND CLINICAL IMPORTANCE Regular low-intensity exercise provided additional health benefits compared with dietary restriction alone in this population of obese equids.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Resistência à Insulina
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Dieta Redutora
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Terapia por Exercício
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Doenças dos Cavalos
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Obesidade
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article