New-Onset Geriatric Epilepsy in China: A Single-Center Study.
Chin Med J (Engl)
; 131(24): 2915-2920, 2018 Dec 20.
Article
em En
| MEDLINE
| ID: mdl-30539903
ABSTRACT
BACKGROUND:
Few studies have been published on new-onset geriatric epilepsy especially in older Chinese people. This study was to have a comprehensive understanding of new-onset geriatric epilepsy and find a more reasonable diagnosis and management of epilepsy in older people.METHODS:
One hundred and three patients with onset age 60 years and older were admitted between January 2008 and December 2016. Electronic medical records were reviewed to collect information.RESULTS:
There were 103 older patients with new-onset epilepsy. The mean age of the patients was 68.5 ± 6.4 years (range 60-89 years), and there were 67 (65%) men and 36 (35%) women. The mean onset age was 67.9 ± 6.2 years (range 60-89 years). The most common identifiable etiology of symptomatic seizures was autoimmune epilepsy in 43 (41.7%) patients. The second most common etiology was stroke in 15 (14.6%) patients. Seven (6.8%) older patients with acute seizures present with status epilepticus and 26 (25.2%) patients experienced clustered seizures (more than three events in 24 h) at seizure onset. Focal seizures (96.1%) were more common than generalized seizures (3.9%). Fifty-three (51.5%) patients had an abnormal brain magnetic resonance imaging (MRI) scan. Among them, video-electroencephalogram findings in 31 (30.1%) patients correlated with MRI abnormalities. Levetiracetam was the most used drugs before admission, in hospital, and during follow-up.CONCLUSIONS:
Autoimmune encephalitis is becoming an increasing risk factor of subsequent epilepsy in older people. Older patients with new epilepsy are more likely to respond to antiepileptic drugs, and drug-resistant epilepsy is uncommon.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Epilepsia
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article