Acquired Nisin Resistance in <i>Staphylococcus aureus</i> Involves Constitutive Activation of an Intrinsic Peptide Antibiotic Detoxification Module.

Randall, Christopher P; Gupta, Arya; Utley-Drew, Bret; Lee, Siu Yi; Morrison-Williams, Genevieve; O'Neill, Alex J

Acquired Nisin Resistance in Staphylococcus aureus Involves Constitutive Activation of an Intrinsic Peptide Antibiotic Detoxification Module.

Randall, Christopher P; Gupta, Arya; Utley-Drew, Bret; Lee, Siu Yi; Morrison-Williams, Genevieve; O'Neill, Alex J.

Afiliação

Randall CP; Antimicrobial Research Centre and School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Gupta A; Antimicrobial Research Centre and School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Utley-Drew B; Antimicrobial Research Centre and School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Lee SY; Antimicrobial Research Centre and School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Morrison-Williams G; Antimicrobial Research Centre and School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
O'Neill AJ; Antimicrobial Research Centre and School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom a.j.oneill@leeds.ac.uk.

mSphere ; 3(6)2018 12 12.

Article em En | MEDLINE | ID: mdl-30541781

Assuntos

Antibacterianos/farmacologia; Farmacorresistência Bacteriana; Inativação Metabólica; Redes e Vias Metabólicas; Nisina/farmacologia; Staphylococcus aureus/efeitos dos fármacos; Antibacterianos/metabolismo; Proteínas de Bactérias/genética; Transporte Biológico; Perfilação da Expressão Gênica; Regulação Bacteriana da Expressão Gênica; Mutação; Nisina/metabolismo; Transdução de Sinais; Staphylococcus aureus/genética

Palavras-chave

bacteriocin; lantibiotic; resistance studies; staphylococci

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Staphylococcus aureus / Inativação Metabólica / Farmacorresistência Bacteriana / Redes e Vias Metabólicas / Antibacterianos / Nisina Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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