Combined Raman- and AFM-based detection of biochemical and nanomechanical features of endothelial dysfunction in aorta isolated from ApoE/LDLR-/- mice.

Maase, Martina; Rygula, Anna; Pacia, Marta Z; Proniewski, Bartosz; Mateuszuk, Lukasz; Sternak, Magdalena; Kaczor, Agnieszka; Chlopicki, Stefan; Kusche-Vihrog, Kristina

Maase, Martina; Rygula, Anna; Pacia, Marta Z; Proniewski, Bartosz; Mateuszuk, Lukasz; Sternak, Magdalena; Kaczor, Agnieszka; Chlopicki, Stefan; Kusche-Vihrog, Kristina.

Afiliação

Maase M; Institute of Physiology II, University of Münster, Robert-Koch Str. 27b, 48149 Münster, Germany.
Rygula A; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, 30-348 Krakow, Poland.
Pacia MZ; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, 30-348 Krakow, Poland; Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387 Krakow, Poland.
Proniewski B; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, 30-348 Krakow, Poland.
Mateuszuk L; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, 30-348 Krakow, Poland.
Sternak M; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, 30-348 Krakow, Poland.
Kaczor A; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, 30-348 Krakow, Poland; Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387 Krakow, Poland.
Chlopicki S; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, 30-348 Krakow, Poland; Chair of Pharmacology, Jagiellonian University, Grzegorzecka 16, 31-531 Krakow, Poland. Electronic address: stefan.chlopicki@jcet.eu.
Kusche-Vihrog K; Institute of Physiology II, University of Münster, Robert-Koch Str. 27b, 48149 Münster, Germany; Institute of Physiology, University of Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany. Electronic address: kristina.kuschevihrog@uni-luebeck.de.

Nanomedicine ; 16: 97-105, 2019 02.

Article em En | MEDLINE | ID: mdl-30550804

Assuntos

Aorta/patologia; Apolipoproteínas E/genética; Endotélio Vascular/patologia; Microscopia de Força Atômica/métodos; Receptores de LDL/genética; Análise Espectral Raman/métodos; Animais; Aorta/metabolismo; Apolipoproteínas E/metabolismo; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Receptores de LDL/metabolismo

Palavras-chave

Atomic force microscopy; Endothelial dysfunction; Endothelial nanomechanics; Hypercholesterolemia; Raman spectroscopy

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aorta / Apolipoproteínas E / Análise Espectral Raman / Receptores de LDL / Endotélio Vascular / Microscopia de Força Atômica Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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