PfVPS45 Is Required for Host Cell Cytosol Uptake by Malaria Blood Stage Parasites.

Jonscher, Ernst; Flemming, Sven; Schmitt, Marius; Sabitzki, Ricarda; Reichard, Nick; Birnbaum, Jakob; Bergmann, Bärbel; Höhn, Katharina; Spielmann, Tobias

Jonscher, Ernst; Flemming, Sven; Schmitt, Marius; Sabitzki, Ricarda; Reichard, Nick; Birnbaum, Jakob; Bergmann, Bärbel; Höhn, Katharina; Spielmann, Tobias.

Afiliação

Jonscher E; Molecular Biology and Immunology Section, Bernhard Nocht Institute for Tropical Medicine, Bernhard Nocht Strasse 74, Hamburg 20359, Germany.
Flemming S; Molecular Biology and Immunology Section, Bernhard Nocht Institute for Tropical Medicine, Bernhard Nocht Strasse 74, Hamburg 20359, Germany.
Schmitt M; Molecular Biology and Immunology Section, Bernhard Nocht Institute for Tropical Medicine, Bernhard Nocht Strasse 74, Hamburg 20359, Germany.
Sabitzki R; Molecular Biology and Immunology Section, Bernhard Nocht Institute for Tropical Medicine, Bernhard Nocht Strasse 74, Hamburg 20359, Germany.
Reichard N; Molecular Biology and Immunology Section, Bernhard Nocht Institute for Tropical Medicine, Bernhard Nocht Strasse 74, Hamburg 20359, Germany.
Birnbaum J; Molecular Biology and Immunology Section, Bernhard Nocht Institute for Tropical Medicine, Bernhard Nocht Strasse 74, Hamburg 20359, Germany.
Bergmann B; Molecular Biology and Immunology Section, Bernhard Nocht Institute for Tropical Medicine, Bernhard Nocht Strasse 74, Hamburg 20359, Germany.
Höhn K; Electron Microscopy Unit, Bernhard Nocht Institute for Tropical Medicine, Bernhard Nocht Strasse 74, Hamburg 20359, Germany.
Spielmann T; Molecular Biology and Immunology Section, Bernhard Nocht Institute for Tropical Medicine, Bernhard Nocht Strasse 74, Hamburg 20359, Germany. Electronic address: spielmann@bni-hamburg.de.

Cell Host Microbe ; 25(1): 166-173.e5, 2019 01 09.

Article em En | MEDLINE | ID: mdl-30581113

Assuntos

Citosol/parasitologia; Eritrócitos/parasitologia; Hemoglobinas/metabolismo; Malária Falciparum/sangue; Malária Falciparum/parasitologia; Plasmodium falciparum/fisiologia; Proteínas de Protozoários/metabolismo; Animais; Transporte Biológico; Citosol/metabolismo; Complexo de Golgi/metabolismo; Interações Hospedeiro-Parasita; Humanos; Parasitos/crescimento & desenvolvimento; Plasmodium falciparum/crescimento & desenvolvimento; Plasmodium falciparum/patogenicidade; Transporte Proteico; Proteínas de Protozoários/genética; Vacúolos/metabolismo; Vacúolos/parasitologia; Vacúolos/ultraestrutura

Palavras-chave

Plasmodium falciparum; VPS45; endocytosis; hemoglobin; host cell cytosol uptake; malaria; molecular parasitology

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Hemoglobinas / Proteínas de Protozoários / Malária Falciparum / Citosol / Eritrócitos Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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