Tricarboxylic acid cycle activity suppresses acetylation of mitochondrial proteins during early embryonic development in <i>Caenorhabditis elegans</i>.

Hada, Kazumasa; Hirota, Keiko; Inanobe, Ai; Kako, Koichiro; Miyata, Mai; Araoi, Sho; Matsumoto, Masaki; Ohta, Reiya; Arisawa, Mitsuhiro; Daitoku, Hiroaki; Hanada, Toshikatsu; Fukamizu, Akiyoshi

Tricarboxylic acid cycle activity suppresses acetylation of mitochondrial proteins during early embryonic development in Caenorhabditis elegans.

Hada, Kazumasa; Hirota, Keiko; Inanobe, Ai; Kako, Koichiro; Miyata, Mai; Araoi, Sho; Matsumoto, Masaki; Ohta, Reiya; Arisawa, Mitsuhiro; Daitoku, Hiroaki; Hanada, Toshikatsu; Fukamizu, Akiyoshi.

Afiliação

Hada K; From the Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8577, Japan.
Hirota K; Department of Cell Biology, Faculty of Medicine, Oita University, 1-1 Hasama-machi Idaigaoka, Yufu, Oita, 879-5593, Japan.
Inanobe A; Ph.D. Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8572, Japan.
Kako K; Faculty of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8572, Japan the.
Miyata M; Department of Hygiene and Public Health, School of Medicine, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan.
Araoi S; Graduate School of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8572, Japan.
Matsumoto M; Ph.D. Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8572, Japan.
Ohta R; Faculty of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8572, Japan the.
Arisawa M; Graduate School of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8572, Japan.
Daitoku H; Graduate School of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8572, Japan.
Hanada T; Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Fukuoka, Fukuoka 812-8582, Japan.
Fukamizu A; Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita, Osaka 565-0871, Japan, and.

J Biol Chem ; 294(9): 3091-3099, 2019 03 01.

Article em En | MEDLINE | ID: mdl-30606736

Assuntos

Caenorhabditis elegans/embriologia; Caenorhabditis elegans/metabolismo; Ciclo do Ácido Cítrico; Desenvolvimento Embrionário; Proteínas Mitocondriais/metabolismo; Acetilação; Trifosfato de Adenosina/metabolismo; Animais; Ácido Aspártico/metabolismo; Caenorhabditis elegans/citologia; Caenorhabditis elegans/genética; Citrato (si)-Sintase/deficiência; Citrato (si)-Sintase/genética; Ácido Cítrico/metabolismo; Ácido Glutâmico/metabolismo; Espaço Intracelular/metabolismo; Fatores de Tempo

Palavras-chave

Caenorhabditis elegans (C. elegans); acetyl coenzyme A (acetyl-CoA); citrate synthase; deacetylase; early embryogenesis; mitochondrial protein acetylation; polyamine; post-translational modification (PTM); sirtuin; tricarboxylic acid cycle (TCA cycle) (Krebs cycle)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ciclo do Ácido Cítrico / Caenorhabditis elegans / Proteínas Mitocondriais / Desenvolvimento Embrionário Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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