Signet ring cell component, not the Lauren subtype, predicts poor survival: an analysis of 198 cases of gastric cancer.
Future Oncol
; 15(4): 401-408, 2019 Feb.
Article
em En
| MEDLINE
| ID: mdl-30620220
ABSTRACT
AIM:
Prognostic differences between major histologic gastric cancer groups, intestinal and diffuse are uncertain, since cellular components in each of them possibly have different behaviors. MATERIALS &METHODS:
We reviewed 198 gastric cancer patients charts diagnosed from January 2003 to December 2015 in a tertiary hospital. Multivariate Cox proportional survival models were used to evaluate the impact of histologic groups on overall survival.RESULTS:
About a third had the signet-ring cell carcinoma (SRCC). In a comparison of the different histologic subtypes, SRCC had the worst prognosis of all. The median durations of survival for patients with stage III and stage IV were 19.7 and 7.7 months, respectively.CONCLUSION:
Signet-ring cell component seem to have a relevant role in defining prognosis for gastric cancer.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Gástricas
/
Carcinoma de Células em Anel de Sinete
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article