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Heterozygous Tbk1 loss has opposing effects in early and late stages of ALS in mice.
Brenner, David; Sieverding, Kirsten; Bruno, Clara; Lüningschrör, Patrick; Buck, Eva; Mungwa, Simon; Fischer, Lena; Brockmann, Sarah J; Ulmer, Johannes; Bliederhäuser, Corinna; Philibert, Clémentine E; Satoh, Takashi; Akira, Shizuo; Boillée, Séverine; Mayer, Benjamin; Sendtner, Michael; Ludolph, Albert C; Danzer, Karin M; Lobsiger, Christian S; Freischmidt, Axel; Weishaupt, Jochen H.
Afiliação
  • Brenner D; Department of Neurology, University of Ulm, Ulm, Germany.
  • Sieverding K; Department of Neurology, University of Ulm, Ulm, Germany.
  • Bruno C; Department of Neurology, University of Ulm, Ulm, Germany.
  • Lüningschrör P; Institute of Clinical Neurobiology, University Hospital of Wuerzburg, Wuerzburg, Germany.
  • Buck E; Department of Neurology, University of Ulm, Ulm, Germany.
  • Mungwa S; Institute of Clinical Neurobiology, University Hospital of Wuerzburg, Wuerzburg, Germany.
  • Fischer L; Department of Neurology, University of Ulm, Ulm, Germany.
  • Brockmann SJ; Department of Neurology, University of Ulm, Ulm, Germany.
  • Ulmer J; Department of Neurology, University of Ulm, Ulm, Germany.
  • Bliederhäuser C; Department of Neurology, University of Ulm, Ulm, Germany.
  • Philibert CE; Institut du Cerveau et de la Moelle Épinière, Institut National de la Santé et de la Recherche Médicale Unité 1127, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 7225, Sorbonne Université, Paris, France.
  • Satoh T; Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
  • Akira S; Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
  • Boillée S; Institut du Cerveau et de la Moelle Épinière, Institut National de la Santé et de la Recherche Médicale Unité 1127, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 7225, Sorbonne Université, Paris, France.
  • Mayer B; Institute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany.
  • Sendtner M; Institute of Clinical Neurobiology, University Hospital of Wuerzburg, Wuerzburg, Germany.
  • Ludolph AC; Department of Neurology, University of Ulm, Ulm, Germany.
  • Danzer KM; Department of Neurology, University of Ulm, Ulm, Germany.
  • Lobsiger CS; Institut du Cerveau et de la Moelle Épinière, Institut National de la Santé et de la Recherche Médicale Unité 1127, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 7225, Sorbonne Université, Paris, France.
  • Freischmidt A; Department of Neurology, University of Ulm, Ulm, Germany.
  • Weishaupt JH; Department of Neurology, University of Ulm, Ulm, Germany jochen.weishaupt@uni-ulm.de.
J Exp Med ; 216(2): 267-278, 2019 02 04.
Article em En | MEDLINE | ID: mdl-30635357
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encéfalo / Proteínas Serina-Treonina Quinases / Deleção de Genes / Esclerose Lateral Amiotrófica / Neurônios Motores Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encéfalo / Proteínas Serina-Treonina Quinases / Deleção de Genes / Esclerose Lateral Amiotrófica / Neurônios Motores Idioma: En Ano de publicação: 2019 Tipo de documento: Article