Development and Characterization of a Self-Nanoemulsifying Drug Delivery System Comprised of Rice Bran Oil for Poorly Soluble Drugs.

Eleftheriadis, Georgios K; Mantelou, Panagiota; Karavasili, Christina; Chatzopoulou, Paschalina; Katsantonis, Dimitrios; Irakli, Maria; Mygdalia, Aggeliki; Vizirianakis, Ioannis S; Fatouros, Dimitrios G

Eleftheriadis, Georgios K; Mantelou, Panagiota; Karavasili, Christina; Chatzopoulou, Paschalina; Katsantonis, Dimitrios; Irakli, Maria; Mygdalia, Aggeliki; Vizirianakis, Ioannis S; Fatouros, Dimitrios G.

Afiliação

Eleftheriadis GK; Laboratory of Pharmaceutical Technology, Department of Pharmacy, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece.
Mantelou P; Laboratory of Pharmaceutical Technology, Department of Pharmacy, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece.
Karavasili C; Laboratory of Pharmaceutical Technology, Department of Pharmacy, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece.
Chatzopoulou P; Hellenic Agricultural Organization Demeter, Plant Breeding and Genetic Resources Institute, Thermi, 57001, Thessaloniki, Greece.
Katsantonis D; Hellenic Agricultural Organization Demeter, Cereal Institute, Thermi, 57001, Thessaloniki, Greece.
Irakli M; Hellenic Agricultural Organization Demeter, Plant Breeding and Genetic Resources Institute, Thermi, 57001, Thessaloniki, Greece.
Mygdalia A; Hellenic Agricultural Organization Demeter, Cereal Institute, Thermi, 57001, Thessaloniki, Greece.
Vizirianakis IS; Laboratory of Pharmacology, School of Pharmacy, Aristotle University of Thessaloniki GR, 54124, Thessaloniki, Greece.
Fatouros DG; Laboratory of Pharmaceutical Technology, Department of Pharmacy, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece. dfatouro@pharm.auth.gr.

AAPS PharmSciTech ; 20(2): 78, 2019 Jan 11.

Article em En | MEDLINE | ID: mdl-30635752

Assuntos

Sistemas de Liberação de Medicamentos/métodos; Emulsificantes/química; Nanopartículas/química; Óleo de Farelo de Arroz/química; Disponibilidade Biológica; Células CACO-2; Sobrevivência Celular/efeitos dos fármacos; Sobrevivência Celular/fisiologia; Portadores de Fármacos/administração & dosagem; Portadores de Fármacos/química; Emulsificantes/administração & dosagem; Excipientes/administração & dosagem; Excipientes/química; Humanos; Nanopartículas/administração & dosagem; Tamanho da Partícula; Óleo de Farelo de Arroz/administração & dosagem; Solubilidade; Tensoativos/química; Água/química

Palavras-chave

SNEDDS; multifactor analysis; poorly soluble drugs; rice bran oil; simulated intestinal fluids

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistemas de Liberação de Medicamentos / Emulsificantes / Nanopartículas / Óleo de Farelo de Arroz Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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