Your browser doesn't support javascript.
loading
In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model.
Carreras, Alba; Pane, Luna Simona; Nitsch, Roberto; Madeyski-Bengtson, Katja; Porritt, Michelle; Akcakaya, Pinar; Taheri-Ghahfarokhi, Amir; Ericson, Elke; Bjursell, Mikael; Perez-Alcazar, Marta; Seeliger, Frank; Althage, Magnus; Knöll, Ralph; Hicks, Ryan; Mayr, Lorenz M; Perkins, Rosie; Lindén, Daniel; Borén, Jan; Bohlooly-Y, Mohammad; Maresca, Marcello.
Afiliação
  • Carreras A; Discovery Biology, Discovery Sciences, IMED Biotech Unit, AstraZeneca, Pepparedsleden 1, Mölndal, 43 183, Gothenburg, Sweden.
  • Pane LS; Present Address: Department of Molecular and Clinical Medicine, University of Gothenburg, The Wallenberg Laboratory, Sahlgrenska University Hospital, Gothenburg, Sweden.
  • Nitsch R; Discovery Biology, Discovery Sciences, IMED Biotech Unit, AstraZeneca, Pepparedsleden 1, Mölndal, 43 183, Gothenburg, Sweden.
  • Madeyski-Bengtson K; Advanced Medicines Safety, Drug Safety and Metabolism, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden.
  • Porritt M; Discovery Biology, Discovery Sciences, IMED Biotech Unit, AstraZeneca, Pepparedsleden 1, Mölndal, 43 183, Gothenburg, Sweden.
  • Akcakaya P; Discovery Biology, Discovery Sciences, IMED Biotech Unit, AstraZeneca, Pepparedsleden 1, Mölndal, 43 183, Gothenburg, Sweden.
  • Taheri-Ghahfarokhi A; Discovery Biology, Discovery Sciences, IMED Biotech Unit, AstraZeneca, Pepparedsleden 1, Mölndal, 43 183, Gothenburg, Sweden.
  • Ericson E; Discovery Biology, Discovery Sciences, IMED Biotech Unit, AstraZeneca, Pepparedsleden 1, Mölndal, 43 183, Gothenburg, Sweden.
  • Bjursell M; Discovery Biology, Discovery Sciences, IMED Biotech Unit, AstraZeneca, Pepparedsleden 1, Mölndal, 43 183, Gothenburg, Sweden.
  • Perez-Alcazar M; Discovery Biology, Discovery Sciences, IMED Biotech Unit, AstraZeneca, Pepparedsleden 1, Mölndal, 43 183, Gothenburg, Sweden.
  • Seeliger F; Pathology Science, Drug Safety and Metabolism, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden.
  • Althage M; Pathology Science, Drug Safety and Metabolism, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden.
  • Knöll R; Cardiovascular, Renal and Metabolism, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden.
  • Hicks R; Cardiovascular, Renal and Metabolism, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden.
  • Mayr LM; Discovery Biology, Discovery Sciences, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden.
  • Perkins R; Discovery Biology, Discovery Sciences, IMED Biotech Unit, AstraZeneca, Pepparedsleden 1, Mölndal, 43 183, Gothenburg, Sweden.
  • Lindén D; Present Address: GE Healthcare Life Sciences, The Grove Centre, White Lion Road, Amersham, UK.
  • Borén J; Department of Molecular and Clinical Medicine, University of Gothenburg, The Wallenberg Laboratory, Sahlgrenska University Hospital, Gothenburg, Sweden.
  • Bohlooly-Y M; Cardiovascular, Renal and Metabolism, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden.
  • Maresca M; Department of Molecular and Clinical Medicine, University of Gothenburg, The Wallenberg Laboratory, Sahlgrenska University Hospital, Gothenburg, Sweden.
BMC Biol ; 17(1): 4, 2019 01 15.
Article em En | MEDLINE | ID: mdl-30646909
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Colesterol / Pró-Proteína Convertase 9 / Hipercolesterolemia / Fígado Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Colesterol / Pró-Proteína Convertase 9 / Hipercolesterolemia / Fígado Idioma: En Ano de publicação: 2019 Tipo de documento: Article