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Association of Smoking and Obesity on the Risk of Developing Primary Sjögren Syndrome: A Population-based Cohort Study.
Servioli, Luisa; Maciel, Gabriel; Nannini, Carlotta; Crowson, Cynthia S; Matteson, Eric L; Cornec, Divi; Berti, Alvise.
Afiliação
  • Servioli L; From the Division of Rheumatology, and Division of Biomedical Statistics and Informatics, and Division of Epidemiology, and Division of Pulmonary and Critical Care Medicine, Department of Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA; Autoimmune Dis
  • Maciel G; L. Servioli, MD, Division of Rheumatology, Mayo Clinic College of Medicine and Science, and Autoimmune diseases Department, Medical Clinic 1, Hospital Maciel; G. Maciel, MD, Autoimmune Diseases Department, Medical Clinic 1, Hospital Maciel; C. Nannini, MD, Division of Rheumatology, Mayo Clinic Colle
  • Nannini C; From the Division of Rheumatology, and Division of Biomedical Statistics and Informatics, and Division of Epidemiology, and Division of Pulmonary and Critical Care Medicine, Department of Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA; Autoimmune Dis
  • Crowson CS; L. Servioli, MD, Division of Rheumatology, Mayo Clinic College of Medicine and Science, and Autoimmune diseases Department, Medical Clinic 1, Hospital Maciel; G. Maciel, MD, Autoimmune Diseases Department, Medical Clinic 1, Hospital Maciel; C. Nannini, MD, Division of Rheumatology, Mayo Clinic Colle
  • Matteson EL; From the Division of Rheumatology, and Division of Biomedical Statistics and Informatics, and Division of Epidemiology, and Division of Pulmonary and Critical Care Medicine, Department of Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA; Autoimmune Dis
  • Cornec D; L. Servioli, MD, Division of Rheumatology, Mayo Clinic College of Medicine and Science, and Autoimmune diseases Department, Medical Clinic 1, Hospital Maciel; G. Maciel, MD, Autoimmune Diseases Department, Medical Clinic 1, Hospital Maciel; C. Nannini, MD, Division of Rheumatology, Mayo Clinic Colle
  • Berti A; From the Division of Rheumatology, and Division of Biomedical Statistics and Informatics, and Division of Epidemiology, and Division of Pulmonary and Critical Care Medicine, Department of Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA; Autoimmune Dis
J Rheumatol ; 46(7): 727-730, 2019 07.
Article em En | MEDLINE | ID: mdl-30647188
ABSTRACT

OBJECTIVE:

To explore the role of smoking and obesity in primary Sjögren syndrome (pSS).

METHODS:

Olmsted County (Minnesota, USA) residents (n = 106) diagnosed with pSS from 2000 to 2015 were compared to 3 controls without pSS and matched for age and sex who were randomly selected from Olmsted County residents.

RESULTS:

Current smokers were less likely to be pSS cases (OR 0.34, 95% CI 0.14-0.85), while there was no association between former smoking and case/control status (OR 1.27, 95% CI 0.80-2.03) compared to never smokers. Smoking status was not associated with antinuclear antibody, anti-SSA, anti-SSB, or rheumatoid factor positivity (p > 0.05). OR for obesity was 0.79 (95% CI 0.48-1.30).

CONCLUSION:

In this population-based study, current smoking was inversely associated with case/control status, while body mass index lacked any association.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fumar / Síndrome de Sjogren / Obesidade Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fumar / Síndrome de Sjogren / Obesidade Idioma: En Ano de publicação: 2019 Tipo de documento: Article