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PTGER3 induces ovary tumorigenesis and confers resistance to cisplatin therapy through up-regulation Ras-MAPK/Erk-ETS1-ELK1/CFTR1 axis.
Rodriguez-Aguayo, Cristian; Bayraktar, Emine; Ivan, Cristina; Aslan, Burcu; Mai, Junhua; He, Guangan; Mangala, Lingegowda S; Jiang, Dahai; Nagaraja, Archana S; Ozpolat, Bulent; Chavez-Reyes, Arturo; Ferrari, Mauro; Mitra, Rahul; Siddik, Zahid H; Shen, Haifa; Yang, Xianbin; Sood, Anil K; Lopez-Berestein, Gabriel.
Afiliação
  • Rodriguez-Aguayo C; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Bayraktar E; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Medical Biology, Faculty of Medicine, University of Gaziantep, Gaziantep 27310, Turkey.
  • Ivan C; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Aslan B; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Mai J; Department of Nanomedicine, Houston Methodist Research Institute, Houston, TX 77030, USA.
  • He G; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Mangala LS; Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Jiang D; Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Nagaraja AS; Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Ozpolat B; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Chavez-Reyes A; Centro de Investigación y Estudios Avanzados del IPN, Unidad Monterrey, Apodaca, NL, CP. 66600, Mexico.
  • Ferrari M; Department of Nanomedicine, Houston Methodist Research Institute, Houston, TX 77030, USA.
  • Mitra R; Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Siddik ZH; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Shen H; Department of Nanomedicine, Houston Methodist Research Institute, Houston, TX 77030, USA.
  • Yang X; AM Biotechnologies LLC, 12521 Gulf Freeway, Houston, TX 77034, USA.
  • Sood AK; Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Gynecologic Oncology, The University of Texas MD Anderson
  • Lopez-Berestein G; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Cancer Biology, The University of Texas MD Ande
EBioMedicine ; 40: 290-304, 2019 Feb.
Article em En | MEDLINE | ID: mdl-30655206
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Transdução de Sinais / Transformação Celular Neoplásica / Cisplatino / Resistencia a Medicamentos Antineoplásicos / Receptores de Prostaglandina E Subtipo EP3 Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Transdução de Sinais / Transformação Celular Neoplásica / Cisplatino / Resistencia a Medicamentos Antineoplásicos / Receptores de Prostaglandina E Subtipo EP3 Idioma: En Ano de publicação: 2019 Tipo de documento: Article