An in-line capillary electrophoresis assay for the high-throughput screening of histone deacetylase inhibitors.

Li, Yue; Fang, Hao; Hou, Zhun; Sang, Lihong; Yang, Xinying

Li, Yue; Fang, Hao; Hou, Zhun; Sang, Lihong; Yang, Xinying.

Afiliação

Li Y; School of Pharmacy, Shandong University, 44 West Wenhua Road, Jinan, Shandong, 250012, China.
Fang H; Department of Medicinal Chemistry and Key Laboratory of Chemical Biology of Natural Products (MOE), School of Pharmacy, Shandong University, 44 West Wenhua Road, Jinan, Shandong, 250012, China.
Hou Z; School of Pharmacy, Shandong University, 44 West Wenhua Road, Jinan, Shandong, 250012, China.
Sang L; School of Pharmacy, Shandong University, 44 West Wenhua Road, Jinan, Shandong, 250012, China.
Yang X; School of Pharmacy, Shandong University, 44 West Wenhua Road, Jinan, Shandong, 250012, China. Electronic address: xinyingyang@sdu.edu.cn.

J Chromatogr A ; 1591: 171-177, 2019 Apr 26.

Article em En | MEDLINE | ID: mdl-30665742

Assuntos

Eletroforese Capilar/métodos; Ensaios de Triagem em Larga Escala/métodos; Inibidores de Histona Desacetilases/análise; Ensaios Enzimáticos; Células HeLa; Histona Desacetilases/metabolismo; Humanos; Cinética; Lisina/análogos & derivados; Reprodutibilidade dos Testes; Especificidade por Substrato

Palavras-chave

Capillary electrophoresis; Electrophoretically mediated microanalysis; Histone deacetylase; Inhibitors; Kinetics

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Eletroforese Capilar / Inibidores de Histona Desacetilases / Ensaios de Triagem em Larga Escala Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google