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ReDO_DB: the repurposing drugs in oncology database.
Pantziarka, Pan; Verbaanderd, Ciska; Sukhatme, Vidula; Rica Capistrano, I; Crispino, Sergio; Gyawali, Bishal; Rooman, Ilse; Van Nuffel, An Mt; Meheus, Lydie; Sukhatme, Vikas P; Bouche, Gauthier.
Afiliação
  • Pantziarka P; The Anticancer Fund, Brussels, 1853 Strombeek-Bever, Belgium.
  • Verbaanderd C; The George Pantziarka TP53 Trust, London, UK.
  • Sukhatme V; The Anticancer Fund, Brussels, 1853 Strombeek-Bever, Belgium.
  • Rica Capistrano I; Clinical Pharmacology and Pharmacotherapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.
  • Crispino S; GlobalCures Inc., Newton, MA 02459 USA.
  • Gyawali B; The Anticancer Fund, Brussels, 1853 Strombeek-Bever, Belgium.
  • Rooman I; The Anticancer Fund, Brussels, 1853 Strombeek-Bever, Belgium.
  • Van Nuffel AM; The Anticancer Fund, Brussels, 1853 Strombeek-Bever, Belgium.
  • Meheus L; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115 USA.
  • Sukhatme VP; The Anticancer Fund, Brussels, 1853 Strombeek-Bever, Belgium.
  • Bouche G; Oncology Research Centre, Vrije Universiteit Brussel, Brussels, Belgium.
Ecancermedicalscience ; 12: 886, 2018.
Article em En | MEDLINE | ID: mdl-30679953
Repurposing is a drug development strategy that seeks to use existing medications for new indications. In oncology, there is an increased level of activity looking at the use of non-cancer drugs as possible cancer treatments. The Repurposing Drugs in Oncology (ReDO) project has used a literature-based approach to identify licensed non-cancer drugs with published evidence of anticancer activity. Data from 268 drugs have been included in a database (ReDO_DB) developed by the ReDO project. Summary results are outlined and an assessment of clinical trial activity also described. The database has been made available as an online open-access resource (http://www.redo-project.org/db/).
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article