Steroids for Acute Vestibular Neuronitis-the Earlier the Treatment, the Better the Outcome?
Otol Neurotol
; 40(3): 372-374, 2019 03.
Article
em En
| MEDLINE
| ID: mdl-30681432
ABSTRACT
OBJECTIVE:
To present findings that suggest steroid treatment within 24âhours of onset of vestibular neuronitis results in better restitution of vestibular function than treatment between 25 and 72âhours. PATIENTS Thirty-three consecutive patients (17 men, 16 women, mean age 57 yr, range 17-85 yr) with acute vestibular neuronitis and treated with steroids within 72âhours after symptom onset. Patients were divided into two groups depending on if they were treated within the first 24âhours or not.INTERVENTIONS:
Oral prednisolone 50âmg/d for 5 days with tapering of doses for the next 5 days, or combined with initial intravenous betamethasone 8âmg the first 1 to 2 days if the patient was nauseous. MAIN OUTCOMEMEASURES:
Proportion of patients with normal caloric test result (canal paresis valueâ<â32%) at follow-up after 3 or 12 months.RESULTS:
All 9 patients (100%) treated within 24âhours from onset of vestibular neuronitis had normal caloric test results at follow-up after 3 months, as compared with 14 of 24 (58%) of the patients treated between 25 and 72âhours (pâ<â0,05, Fisher's exact test).CONCLUSIONS:
The timing of steroid treatment of vestibular neuronitis may be of importance for subsequent vestibular restitution, and hence, for both time to recovery and late symptoms according to the literature.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Prednisolona
/
Neuronite Vestibular
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article