The long non-coding RNA Linc-GALH promotes hepatocellular carcinoma metastasis via epigenetically regulating Gankyrin.

Xu, Xiaoliang; Lou, Yun; Tang, Junwei; Teng, Yue; Zhang, Zechuan; Yin, Yin; Zhuo, Han; Tan, Zhongming

Xu, Xiaoliang; Lou, Yun; Tang, Junwei; Teng, Yue; Zhang, Zechuan; Yin, Yin; Zhuo, Han; Tan, Zhongming.

Afiliação

Xu X; Medical School of Southeast University, Nanjing, Jiangsu, P.R. China.
Lou Y; Department of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, 210093, Jiangsu Province, P.R. China.
Tang J; Department of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, 210093, Jiangsu Province, P.R. China.
Teng Y; Key Laboratory of Living Donor Liver Transplantation, Department of Liver Surgery, National Health and Family Planning Commission, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, P.R. China.
Zhang Z; Key Laboratory of Living Donor Liver Transplantation, Department of Liver Surgery, National Health and Family Planning Commission, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, P.R. China.
Yin Y; Department of Medical Oncology, Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & Nanjing Medical University Affiliated Cancer Hospital, Nanjing, 210009, Jiangsu, P.R. China.
Zhuo H; Department of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, 210093, Jiangsu Province, P.R. China.
Tan Z; Key Laboratory of Living Donor Liver Transplantation, Department of Liver Surgery, National Health and Family Planning Commission, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, P.R. China.

Cell Death Dis ; 10(2): 86, 2019 01 28.

Article em En | MEDLINE | ID: mdl-30692513

Assuntos

Carcinoma Hepatocelular/genética; Neoplasias Hepáticas/genética; Complexo de Endopeptidases do Proteassoma/genética; Proteínas Proto-Oncogênicas/genética; RNA Longo não Codificante/genética; Animais; Carcinoma Hepatocelular/metabolismo; Carcinoma Hepatocelular/patologia; Linhagem Celular Tumoral; DNA (Citosina-5-)-Metiltransferase 1/genética; DNA (Citosina-5-)-Metiltransferase 1/metabolismo; Metilação de DNA; Células Hep G2; Xenoenxertos; Humanos; Imuno-Histoquímica; Neoplasias Hepáticas/metabolismo; Neoplasias Hepáticas/patologia; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/metabolismo; Neoplasias Pulmonares/secundário; Masculino; Camundongos; Metástase Neoplásica; Complexo de Endopeptidases do Proteassoma/metabolismo; Proteínas Proto-Oncogênicas/metabolismo; Proteínas Proto-Oncogênicas c-akt/genética; Proteínas Proto-Oncogênicas c-akt/metabolismo; Transdução de Sinais; Regulação para Cima

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas / Carcinoma Hepatocelular / Complexo de Endopeptidases do Proteassoma / RNA Longo não Codificante / Neoplasias Hepáticas Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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