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Single molecule glycosylase studies with engineered 8-oxoguanine DNA damage sites show functional defects of a MUTYH polyposis variant.
Nelson, Shane R; Kathe, Scott D; Hilzinger, Thomas S; Averill, April M; Warshaw, David M; Wallace, Susan S; Lee, Andrea J.
Afiliação
  • Nelson SR; Department of Molecular Physiology and Biophysics, Robert Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA.
  • Kathe SD; Department of Microbiology and Molecular Genetics, Robert Larner College of Medicine and College of Agriculture and Life Sciences, University of Vermont, Burlington, VT 05405, USA.
  • Hilzinger TS; Department of Microbiology and Molecular Genetics, Robert Larner College of Medicine and College of Agriculture and Life Sciences, University of Vermont, Burlington, VT 05405, USA.
  • Averill AM; Department of Microbiology and Molecular Genetics, Robert Larner College of Medicine and College of Agriculture and Life Sciences, University of Vermont, Burlington, VT 05405, USA.
  • Warshaw DM; Department of Molecular Physiology and Biophysics, Robert Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA.
  • Wallace SS; Department of Microbiology and Molecular Genetics, Robert Larner College of Medicine and College of Agriculture and Life Sciences, University of Vermont, Burlington, VT 05405, USA.
  • Lee AJ; Department of Microbiology and Molecular Genetics, Robert Larner College of Medicine and College of Agriculture and Life Sciences, University of Vermont, Burlington, VT 05405, USA.
Nucleic Acids Res ; 47(6): 3058-3071, 2019 04 08.
Article em En | MEDLINE | ID: mdl-30698731

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dano ao DNA / Neoplasias Colorretais / Polipose Adenomatosa do Colo / DNA Glicosilases Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dano ao DNA / Neoplasias Colorretais / Polipose Adenomatosa do Colo / DNA Glicosilases Idioma: En Ano de publicação: 2019 Tipo de documento: Article