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The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells.
Perucha, Esperanza; Melchiotti, Rossella; Bibby, Jack A; Wu, Wing; Frederiksen, Klaus Stensgaard; Roberts, Ceri A; Hall, Zoe; LeFriec, Gaelle; Robertson, Kevin A; Lavender, Paul; Gerwien, Jens Gammeltoft; Taams, Leonie S; Griffin, Julian L; de Rinaldis, Emanuele; van Baarsen, Lisa G M; Kemper, Claudia; Ghazal, Peter; Cope, Andrew P.
Afiliação
  • Perucha E; Academic Department of Rheumatology, King's College London, London, SE1 1UL, UK. esperanza.perucha@kcl.ac.uk.
  • Melchiotti R; Department of Inflammation Biology, School of Immunology and Microbial Sciences, Centre for Inflammation Biology and Cancer Immunology, King's College London, London, SE1 1UL, UK. esperanza.perucha@kcl.ac.uk.
  • Bibby JA; National Institute for Health Research Biomedical Research Centre, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, SE1 9RT, UK.
  • Wu W; Academic Department of Rheumatology, King's College London, London, SE1 1UL, UK.
  • Frederiksen KS; Department of Inflammation Biology, School of Immunology and Microbial Sciences, Centre for Inflammation Biology and Cancer Immunology, King's College London, London, SE1 1UL, UK.
  • Roberts CA; Academic Department of Rheumatology, King's College London, London, SE1 1UL, UK.
  • Hall Z; Department of Inflammation Biology, School of Immunology and Microbial Sciences, Centre for Inflammation Biology and Cancer Immunology, King's College London, London, SE1 1UL, UK.
  • LeFriec G; Global Drug Discovery, Novo Nordisk A/S, 2880, Bagsvaerd, Denmark.
  • Robertson KA; Department of Inflammation Biology, School of Immunology and Microbial Sciences, Centre for Inflammation Biology and Cancer Immunology, King's College London, London, SE1 1UL, UK.
  • Lavender P; Cellular and Molecular Therapy, NHS Blood and Transplant, Bristol, BS34 7QH, UK.
  • Gerwien JG; Department of Biochemistry and the Cambridge Systems Biology Centre, University of Cambridge, Cambridge, CB2 1QW, UK.
  • Taams LS; MRC Centre for Transplantation, King's College London, London, SE1 9RT, UK.
  • Griffin JL; Division of Infection and Pathway Medicine, University of Edinburgh, Edinburgh, EH16 4SB, UK.
  • de Rinaldis E; School of Immunology and Microbial Sciences, King's College London, London, SE1 9RT, UK.
  • van Baarsen LGM; Global Drug Discovery, Novo Nordisk A/S, 2880, Bagsvaerd, Denmark.
  • Kemper C; Rheumatology NEC, Eli Lilly, 2730, Copenhagen, Denmark.
  • Ghazal P; Department of Inflammation Biology, School of Immunology and Microbial Sciences, Centre for Inflammation Biology and Cancer Immunology, King's College London, London, SE1 1UL, UK.
  • Cope AP; Department of Biochemistry and the Cambridge Systems Biology Centre, University of Cambridge, Cambridge, CB2 1QW, UK.
Nat Commun ; 10(1): 498, 2019 01 30.
Article em En | MEDLINE | ID: mdl-30700717
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Colesterol / Interferon gama / Interleucina-10 / Células Th1 Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Colesterol / Interferon gama / Interleucina-10 / Células Th1 Idioma: En Ano de publicação: 2019 Tipo de documento: Article