Mendelian randomisation: A powerful and inexpensive method for identifying and excluding non-genetic risk factors for colorectal cancer.

Cornish, Alex J; Tomlinson, Ian P M; Houlston, Richard S

Cornish, Alex J; Tomlinson, Ian P M; Houlston, Richard S.

Afiliação

Cornish AJ; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK. Electronic address: alex.cornish@icr.ac.uk.
Tomlinson IPM; Cancer Genetics and Evolution Laboratory, Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK; Department of Histopathology, University Hospitals Birmingham, Birmingham, UK.
Houlston RS; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK; Division of Molecular Pathology, The Institute of Cancer Research, London, UK.

Mol Aspects Med ; 69: 41-47, 2019 10.

Article em En | MEDLINE | ID: mdl-30710596

Assuntos

Neoplasias Colorretais/etiologia; Suscetibilidade a Doenças; Predisposição Genética para Doença; Neoplasias Colorretais/diagnóstico; Humanos; Análise da Randomização Mendeliana; Medição de Risco; Fatores de Risco

Palavras-chave

Causal relationship; Colorectal cancer; Genetic variants; Instrumental variables; Mendelian randomisation; Risk factors

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Predisposição Genética para Doença / Suscetibilidade a Doenças Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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