Dysregulation of HDAC9 Represses Trophoblast Cell Migration and Invasion Through TIMP3 Activation in Preeclampsia.

Xie, Dandan; Zhu, Jingping; Liu, Qianqian; Li, Jun; Song, Mengjiu; Wang, Kai; Zhou, Qian; Jia, Yuanhui; Li, Ting

Xie, Dandan; Zhu, Jingping; Liu, Qianqian; Li, Jun; Song, Mengjiu; Wang, Kai; Zhou, Qian; Jia, Yuanhui; Li, Ting.

Afiliação

Xie D; Department of Obstetrics, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.
Zhu J; Department of Obstetrics, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.
Liu Q; Department of Obstetrics, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.
Li J; Department of Obstetrics, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.
Song M; Department of Obstetrics, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.
Wang K; Clinical and Translational Research Center, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.
Zhou Q; Clinical and Translational Research Center, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.
Jia Y; Clinical and Translational Research Center, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.
Li T; Department of Obstetrics, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.

Am J Hypertens ; 32(5): 515-523, 2019 04 22.

Article em En | MEDLINE | ID: mdl-30715128

Assuntos

Regulação da Expressão Gênica; Histona Desacetilases/genética; Pré-Eclâmpsia/genética; RNA/genética; Proteínas Repressoras/genética; Inibidor Tecidual de Metaloproteinase-3/genética; Trofoblastos/patologia; Adulto; Western Blotting; Linhagem Celular; Movimento Celular; Proliferação de Células; Progressão da Doença; Regulação para Baixo; Feminino; Idade Gestacional; Histona Desacetilases/biossíntese; Humanos; Imuno-Histoquímica; Pré-Eclâmpsia/metabolismo; Pré-Eclâmpsia/patologia; Gravidez; Proteínas Repressoras/biossíntese; Transdução de Sinais; Inibidor Tecidual de Metaloproteinase-3/metabolismo; Trofoblastos/metabolismo; Regulação para Cima

Palavras-chave

HDAC9; TIMP3; blood pressure; histone acetylation; hypertension; preeclampsia; trophoblast cell migration and invasion

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pré-Eclâmpsia / Proteínas Repressoras / Trofoblastos / RNA / Regulação da Expressão Gênica / Inibidor Tecidual de Metaloproteinase-3 / Histona Desacetilases Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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