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Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation.
Czechowicz, Agnieszka; Palchaudhuri, Rahul; Scheck, Amelia; Hu, Yu; Hoggatt, Jonathan; Saez, Borja; Pang, Wendy W; Mansour, Michael K; Tate, Tiffany A; Chan, Yan Yi; Walck, Emily; Wernig, Gerlinde; Shizuru, Judith A; Winau, Florian; Scadden, David T; Rossi, Derrick J.
Afiliação
  • Czechowicz A; Program in Cellular and Molecular Medicine, Department of Medicine, Boston Children's Hospital, Boston, MA, 02115, USA. aneeshka@stanford.edu.
  • Palchaudhuri R; Department of Pediatric Oncology, Dana Farber Cancer Institute, Boston, MA, 02115, USA. aneeshka@stanford.edu.
  • Scheck A; Department of Pediatrics, Division of Hematology/Oncology, Harvard Medical School, Boston, MA, 02115, USA. aneeshka@stanford.edu.
  • Hu Y; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, 02138, USA. aneeshka@stanford.edu.
  • Hoggatt J; Harvard Stem Cell Institute, Cambridge, MA, 02138, USA. aneeshka@stanford.edu.
  • Saez B; Department of Pediatrics, Division of Stem Cell Transplantation and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA. aneeshka@stanford.edu.
  • Pang WW; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA. aneeshka@stanford.edu.
  • Mansour MK; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, 02138, USA.
  • Tate TA; Harvard Stem Cell Institute, Cambridge, MA, 02138, USA.
  • Chan YY; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA.
  • Walck E; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, 02138, USA.
  • Wernig G; Magenta Therapeutics, Cambridge, MA, 02139, USA.
  • Shizuru JA; Program in Cellular and Molecular Medicine, Department of Medicine, Boston Children's Hospital, Boston, MA, 02115, USA.
  • Winau F; Department of Pediatrics, Division of Hematology/Oncology, Harvard Medical School, Boston, MA, 02115, USA.
  • Scadden DT; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, 02138, USA.
  • Rossi DJ; Harvard Stem Cell Institute, Cambridge, MA, 02138, USA.
Nat Commun ; 10(1): 617, 2019 02 06.
Article em En | MEDLINE | ID: mdl-30728354
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Hematopoéticas / Imunoconjugados / Transplante de Células-Tronco Hematopoéticas / Proteínas Proto-Oncogênicas c-kit Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Hematopoéticas / Imunoconjugados / Transplante de Células-Tronco Hematopoéticas / Proteínas Proto-Oncogênicas c-kit Idioma: En Ano de publicação: 2019 Tipo de documento: Article