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TNF-α/STAT3 pathway epigenetically upregulates Nav1.6 expression in DRG and contributes to neuropathic pain induced by L5-VRT.
Ding, Huan-Huan; Zhang, Su-Bo; Lv, You-You; Ma, Chao; Liu, Meng; Zhang, Kui-Bo; Ruan, Xiang-Cai; Wei, Jia-You; Xin, Wen-Jun; Wu, Shao-Ling.
Afiliação
  • Ding HH; Neuroscience Program, Zhongshan School of Medicine, the Fifth Affiliated Hospital of Sun Yat-sen University, Sun Yat-sen University, Guangzhou, 510080, China.
  • Zhang SB; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Department of Rehabilitation Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang West Road, Guangzhou, 510120, Guangdong, China.
  • Lv YY; Neuroscience Program, Zhongshan School of Medicine, the Fifth Affiliated Hospital of Sun Yat-sen University, Sun Yat-sen University, Guangzhou, 510080, China.
  • Ma C; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Department of Rehabilitation Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang West Road, Guangzhou, 510120, Guangdong, China.
  • Liu M; Neuroscience Program, Zhongshan School of Medicine, the Fifth Affiliated Hospital of Sun Yat-sen University, Sun Yat-sen University, Guangzhou, 510080, China.
  • Zhang KB; Neuroscience Program, Zhongshan School of Medicine, the Fifth Affiliated Hospital of Sun Yat-sen University, Sun Yat-sen University, Guangzhou, 510080, China.
  • Ruan XC; Department of Anesthesia and Pain Medicine, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, 510120, China.
  • Wei JY; Neuroscience Program, Zhongshan School of Medicine, the Fifth Affiliated Hospital of Sun Yat-sen University, Sun Yat-sen University, Guangzhou, 510080, China.
  • Xin WJ; Neuroscience Program, Zhongshan School of Medicine, the Fifth Affiliated Hospital of Sun Yat-sen University, Sun Yat-sen University, Guangzhou, 510080, China.
  • Wu SL; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Department of Rehabilitation Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang West Road, Guangzhou, 510120, Guangdong, China. wushaolinggz@126.com.
J Neuroinflammation ; 16(1): 29, 2019 Feb 08.
Article em En | MEDLINE | ID: mdl-30736806
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Fator de Necrose Tumoral alfa / Epigênese Genética / Fator de Transcrição STAT3 / Canal de Sódio Disparado por Voltagem NAV1.6 / Gânglios Espinais / Neuralgia Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Fator de Necrose Tumoral alfa / Epigênese Genética / Fator de Transcrição STAT3 / Canal de Sódio Disparado por Voltagem NAV1.6 / Gânglios Espinais / Neuralgia Idioma: En Ano de publicação: 2019 Tipo de documento: Article