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Evaluation of the Abbott ARCHITECT™ cytomegalovirus IgM/IgG, rubella IgM/IgG, and syphilis treponemal antibodies enzyme immunoassays in a mother and child health center population.
Grandjean Lapierre, Simon; Vallières, Emilie; Rabaamad, Leila; Labrecque, Manon; Chartrand, Caroline; Renaud, Christian.
Afiliação
  • Grandjean Lapierre S; Center de Recherche du Centre Hospitalier de l'Université de Montréal, 900 Saint-Denis, Montreal, Quebec, Canada, H2X 0A9; Université de Montréal, 2900 Boulevard Édouard-Montpetit, Montréal, Québec, Canada, H3T 1J4. Electronic address: Simon.grandjean.lapierre@umontreal.ca.
  • Vallières E; Université de Montréal, 2900 Boulevard Édouard-Montpetit, Montréal, Québec, Canada, H3T 1J4; Centre Hospitalier Universitaire Sainte-Justine, 3175 Chemin de la Côte Sainte-Catherine, Montreal, Quebec, Canada, H3T 1C4.
  • Rabaamad L; Centre Hospitalier Universitaire Sainte-Justine, 3175 Chemin de la Côte Sainte-Catherine, Montreal, Quebec, Canada, H3T 1C4.
  • Labrecque M; Centre Hospitalier Universitaire Sainte-Justine, 3175 Chemin de la Côte Sainte-Catherine, Montreal, Quebec, Canada, H3T 1C4.
  • Chartrand C; Université de Montréal, 2900 Boulevard Édouard-Montpetit, Montréal, Québec, Canada, H3T 1J4; Centre Hospitalier Universitaire Sainte-Justine, 3175 Chemin de la Côte Sainte-Catherine, Montreal, Quebec, Canada, H3T 1C4.
  • Renaud C; Université de Montréal, 2900 Boulevard Édouard-Montpetit, Montréal, Québec, Canada, H3T 1J4; Centre Hospitalier Universitaire Sainte-Justine, 3175 Chemin de la Côte Sainte-Catherine, Montreal, Quebec, Canada, H3T 1C4.
Diagn Microbiol Infect Dis ; 94(3): 231-235, 2019 Jul.
Article em En | MEDLINE | ID: mdl-30738692
This study evaluated the concordance of Architect™ chemiluminescent microparticle immunoassays with Captia™ ELISA for cytomegalovirus (CMV) IgM and IgG, with Enzygnost™ and Captia™ ELISA for rubella IgM and IgG and with Trep-Sure™ ELISA for syphilis treponemal antibodies in a mixed pediatric and obstetrical population. Total agreement between assays and Kappa statistic value were 82.5% (95% CI: 75.6-87.7) and 0.65 (95% CI: 0.54-0.77) for CMV IgM, 82.8% (95% CI: 76.7-87.6) and 0.65 (95% CI: 0.55-0.75) for CMV IgG, 89.2% (95% CI: 82.9-93.4) and 0.56 (95% CI: 0.36-0.75) for rubella IgM, 88.6% (95% CI: 82.9-92.6) and 0.74 (95% CI: 0.63-0.84) for rubella IgG, and 97.9% (95% CI: 94.5-99.4) and 0.89 (95% CI: 0.79-1.00) for syphilis treponemal antibodies. This study demonstrates that the Architect™ chemiluminescent microparticle immunoassays correlate well with other FDA-approved ELISA assays in this specific population.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rubéola (Sarampo Alemão) / Sífilis / Técnicas Imunoenzimáticas / Infecções por Citomegalovirus / Testes Diagnósticos de Rotina / Anticorpos Antibacterianos / Anticorpos Antivirais Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rubéola (Sarampo Alemão) / Sífilis / Técnicas Imunoenzimáticas / Infecções por Citomegalovirus / Testes Diagnósticos de Rotina / Anticorpos Antibacterianos / Anticorpos Antivirais Idioma: En Ano de publicação: 2019 Tipo de documento: Article