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Stepwise approach towards adoption of allergen immunotherapy for allergic rhinitis and asthma patients in daily practice in Belgium: a BelSACI-Abeforcal-EUFOREA statement.
Hellings, P W; Pugin, B; Mariën, G; Bachert, C; Breynaert, C; Bullens, D M; Ceuppens, J L; Clement, G; Cox, T; Ebo, D; Gevaert, P; Halewyck, S; Hox, V; Ladha, K; Jacobs, R; Rombaux, P; Schrijvers, R; Speleman, K; Van der Brempt, X; Van Gerven, L; Vanderveken, O; Verhaeghe, B; Vierstraete, K; Vlaminck, S; Watelet, J-B; Bousquet, J; Seys, S F.
Afiliação
  • Hellings PW; 1ENT Clinical Department, University Hospital Leuven, Kapucijnenvoer 33, 3000 Louvain, Belgium.
  • Pugin B; 2Laboratory of Clinical Immunology, Department of Microbiology and Immunology, KU Leuven, Louvain, Belgium.
  • Mariën G; 2Laboratory of Clinical Immunology, Department of Microbiology and Immunology, KU Leuven, Louvain, Belgium.
  • Bachert C; European Forum for Research and Education in Allergy and Airway Diseases, Brussels, Belgium.
  • Breynaert C; European Forum for Research and Education in Allergy and Airway Diseases, Brussels, Belgium.
  • Bullens DM; 4ENT Clinical Department, University Hospital Ghent, Ghent, Belgium.
  • Ceuppens JL; 5Upper Airways Research Laboratory, University of Ghent, Ghent, Belgium.
  • Clement G; 2Laboratory of Clinical Immunology, Department of Microbiology and Immunology, KU Leuven, Louvain, Belgium.
  • Cox T; 6Internal Medicine Clinical Department, UZ Leuven, Louvain, Belgium.
  • Ebo D; 7Pediatrics Clinical Department, UZ Leuven, Louvain, Belgium.
  • Gevaert P; 2Laboratory of Clinical Immunology, Department of Microbiology and Immunology, KU Leuven, Louvain, Belgium.
  • Halewyck S; 6Internal Medicine Clinical Department, UZ Leuven, Louvain, Belgium.
  • Hox V; 8ENT Clinical Department, AZ Damiaan, Ostend, Belgium.
  • Ladha K; 9ENT Clinical Department, Jessa Hospital, Hasselt, Belgium.
  • Jacobs R; 10Immunology-Allergology-Rheumatology, University Hospital Antwerp, Antwerp, Belgium.
  • Rombaux P; 4ENT Clinical Department, University Hospital Ghent, Ghent, Belgium.
  • Schrijvers R; 5Upper Airways Research Laboratory, University of Ghent, Ghent, Belgium.
  • Speleman K; 11ENT Clinical Department, UZ Brussel, Brussels, Belgium.
  • Van der Brempt X; ENT Clinical Department, ASZ Aalst, Aalst, Belgium.
  • Van Gerven L; 13ENT Clinical Department, Clinique Universitaires Saint-Luc, Brussels, Belgium.
  • Vanderveken O; 14Pediatrics Clinical Department, CHU Charleroi, Charleroi, Belgium.
  • Verhaeghe B; 15ENT Clinical Department, AZ Sint-Blasius, Dendermonde, Belgium.
  • Vierstraete K; 13ENT Clinical Department, Clinique Universitaires Saint-Luc, Brussels, Belgium.
  • Vlaminck S; 2Laboratory of Clinical Immunology, Department of Microbiology and Immunology, KU Leuven, Louvain, Belgium.
  • Watelet JB; 6Internal Medicine Clinical Department, UZ Leuven, Louvain, Belgium.
  • Bousquet J; 16ENT Clinical Department, AZ Sint-Jan, Brugge, Belgium.
  • Seys SF; Allergopole, Clinique Saint-Luc Bouge, Namur, Belgium.
Clin Transl Allergy ; 9: 1, 2019.
Article em En | MEDLINE | ID: mdl-30740211
ABSTRACT
Allergic rhinitis (AR) affects 23-30% of the European population with equal prevalence reported in Belgium. Despite guidelines on the correct use of effective treatment, up to 40% of AR patients remain uncontrolled. Allergen immunotherapy (AIT) has been shown to improve the level of control up to 84% of patients being controlled by AIT. Recently, new guidelines for AIT have been published, supporting the clinical evidence for effectiveness of various subcutaneous and sublingual products for AIT in patients who are allergic to airborne allergens. AIT in AR patients not only reduces nasal and/or ocular symptoms but also induces tolerance and has preventive potential. Adoption of AIT into daily clinical practice in Belgium and other European countries is hampered primarily by reimbursement issues of each of the single products but also by several patient- and physician-related factors. Patients need to be better informed about the effectiveness of AIT and the different routes of administration of AIT. Physicians dealing with AR patients should inform patients on tolerance-inducing effects of AIT and are in the need of a harmonized and practical guide that supports them in selecting eligible patients for AIT, in choosing evidence-based AIT products and in following treatment protocols with proven efficacy. Therefore, a stepwise and holistic approach is needed for better adoption of AIT in the real-life setting in Belgium.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2019 Tipo de documento: Article