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Drug sensitivity testing on patient-derived sarcoma cells predicts patient response to treatment and identifies c-Sarc inhibitors as active drugs for translocation sarcomas.
Brodin, Bertha A; Wennerberg, Krister; Lidbrink, Elisabet; Brosjö, Otte; Potdar, Swapnil; Wilson, Jennifer N; Ma, Limin; Moens, Lotte N; Hesla, Asle; Porovic, Edvin; Bernhardsson, Edvin; Papakonstantinou, Antroula; Bauer, Henrik; Tsagkozis, Panagiotis; von Sivers, Karin; Wejde, Johan; Östling, Päivi; Kallioniemi, Olli; Stragliotto, Christina Linder.
Afiliação
  • Brodin BA; Department of Microbiology Tumor and Cell Biology (MTC), Karolinska Institutet, Stockholm, Sweden. bertha.brodin@ki.se.
  • Wennerberg K; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Lidbrink E; Biotech Research and Innovation Center (BRIC), University of Copenhagen, Copenhagen, Denmark.
  • Brosjö O; Department of Breast cancer, Endocrine tumors and Sarcoma, Karolinska University Hospital, Stockholm, Sweden.
  • Potdar S; Department of Tumor Orthopedics, Karolinska University Hospital, Stockholm, Sweden.
  • Wilson JN; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Ma L; Department of Microbiology Tumor and Cell Biology (MTC), Karolinska Institutet, Stockholm, Sweden.
  • Moens LN; Department of Microbiology Tumor and Cell Biology (MTC), Karolinska Institutet, Stockholm, Sweden.
  • Hesla A; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
  • Porovic E; Department of Tumor Orthopedics, Karolinska University Hospital, Stockholm, Sweden.
  • Bernhardsson E; Department of Microbiology Tumor and Cell Biology (MTC), Karolinska Institutet, Stockholm, Sweden.
  • Papakonstantinou A; Department of Microbiology Tumor and Cell Biology (MTC), Karolinska Institutet, Stockholm, Sweden.
  • Bauer H; Department of Breast cancer, Endocrine tumors and Sarcoma, Karolinska University Hospital, Stockholm, Sweden.
  • Tsagkozis P; Department of Oncology - Pathology, Karolinska Institutet, Stockholm, Sweden.
  • von Sivers K; Department of Tumor Orthopedics, Karolinska University Hospital, Stockholm, Sweden.
  • Wejde J; Department of Tumor Orthopedics, Karolinska University Hospital, Stockholm, Sweden.
  • Östling P; Department of Oncology - Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Kallioniemi O; Department of Radiology, Karolinska University Hospital, Stockholm, Sweden.
  • Stragliotto CL; Department of Cytology and Pathology, Karolinska University Hospital, Stockholm, Sweden.
Br J Cancer ; 120(4): 435-443, 2019 02.
Article em En | MEDLINE | ID: mdl-30745580

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sarcoma / Quinases da Família src Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sarcoma / Quinases da Família src Idioma: En Ano de publicação: 2019 Tipo de documento: Article