Computational characterization of enzyme-bound thiamin diphosphate reveals a surprisingly stable tricyclic state: implications for catalysis.

Planas, Ferran; McLeish, Michael J; Himo, Fahmi.

Afiliação

Planas F; Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, SE-10691 Stockholm, Sweden.
McLeish MJ; Department of Chemistry and Chemical Biology, Indiana University-Purdue University Indianapolis, Indianapolis IN 46202, USA.
Himo F; Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, SE-10691 Stockholm, Sweden.

Beilstein J Org Chem ; 15: 145-159, 2019.

Article em En | MEDLINE | ID: mdl-30745990