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In Silico Identification and Experimental Validation of (-)-Muqubilin A, a Marine Norterpene Peroxide, as PPARα/γ-RXRα Agonist and RARα Positive Allosteric Modulator.
D'Aniello, Enrico; Iannotti, Fabio Arturo; Falkenberg, Lauren G; Martella, Andrea; Gentile, Alessandra; De Maio, Fabrizia; Ciavatta, Maria Letizia; Gavagnin, Margherita; Waxman, Joshua S; Di Marzo, Vincenzo; Amodeo, Pietro; Vitale, Rosa Maria.
Afiliação
  • D'Aniello E; Department of Biology and Evolution of Marine Organisms, Stazione Zoologica "Anton Dohrn", 80121 Naples, Italy. enrico.daniello@szn.it.
  • Iannotti FA; Endocannabinoid Research Group (ERG), Institute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078 Pozzuoli (NA), Italy. enrico.daniello@szn.it.
  • Falkenberg LG; Endocannabinoid Research Group (ERG), Institute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078 Pozzuoli (NA), Italy. fabio.iannotti@icb.cnr.it.
  • Martella A; Institute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078 Pozzuoli (NA), Italy. fabio.iannotti@icb.cnr.it.
  • Gentile A; Molecular Cardiovascular Biology Division, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA. lauren.falkenberg@cchmc.org.
  • De Maio F; Institute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078 Pozzuoli (NA), Italy. a.martella@lacdr.leidenuniv.nl.
  • Ciavatta ML; Institute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078 Pozzuoli (NA), Italy. alessandra.gentile@mpi-bn.mpg.de.
  • Gavagnin M; Institute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078 Pozzuoli (NA), Italy. fabriziademaio@yahoo.it.
  • Waxman JS; Institute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078 Pozzuoli (NA), Italy. lciavatta@icb.cnr.it.
  • Di Marzo V; Institute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078 Pozzuoli (NA), Italy. mgavagnin@icb.cnr.it.
  • Amodeo P; Molecular Cardiovascular Biology Division, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA. Joshua.Waxman@cchmc.org.
  • Vitale RM; Endocannabinoid Research Group (ERG), Institute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078 Pozzuoli (NA), Italy. vdimarzo@icb.cnr.it.
Mar Drugs ; 17(2)2019 Feb 12.
Article em En | MEDLINE | ID: mdl-30759808
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peróxidos / Terpenos / PPAR alfa / PPAR gama / Receptor alfa de Ácido Retinoico Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peróxidos / Terpenos / PPAR alfa / PPAR gama / Receptor alfa de Ácido Retinoico Idioma: En Ano de publicação: 2019 Tipo de documento: Article