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Association of incident dialysis modality with mortality: a protocol for systematic review and meta-analysis of randomized controlled trials and cohort studies.
Marshall, Mark R; Hsiao, Chun-Yuan; Li, Philip K; Nakayama, Masaaki; Rabindranath, S; Walker, Rachael C; Yu, Xueqing; Palmer, Suetonia C.
Afiliação
  • Marshall MR; School of Medicine, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand. Mark.Marshall@middlemore.co.nz.
  • Hsiao CY; Department of Renal Medicine, Middlemore Hospital, Counties Manukau Health, Auckland, New Zealand. Mark.Marshall@middlemore.co.nz.
  • Li PK; Baxter Healthcare (Asia) Pte Ltd, Singapore, Singapore. Mark.Marshall@middlemore.co.nz.
  • Nakayama M; Department of Renal Medicine, Middlemore Hospital, Counties Manukau Health, Auckland, New Zealand.
  • Rabindranath S; Department of Medicine & Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
  • Walker RC; Research Division of Chronic Kidney Disease and Dialysis Treatment, Tohoku University Hospital, Sendai, Japan.
  • Yu X; Nephrology Department, St Lukes International Hospital, Tokyo, Japan.
  • Palmer SC; Department of Nephrology, Waikato District Hospital, Hamilton, New Zealand.
Syst Rev ; 8(1): 55, 2019 02 19.
Article em En | MEDLINE | ID: mdl-30782218
ABSTRACT

BACKGROUND:

At least 2.6 million adults and children receive dialysis treatment for end-stage kidney disease (ESKD) worldwide. The large majority of these receive hemodialysis (HD), while the remaining receive peritoneal dialysis (PD). Peritoneal dialysis may be associated with similar mortality outcomes as HD, and patient-reported outcomes are potentially increased with PD. Existing evidence for the mortality associated with PD was summarized over 20 years ago, and there has been greater marginal improvement in survival with PD relative to HD since that time. It is therefore timely to reexamine the question of differential mortality by modality and summarize evidence from more contemporary practice settings. METHODS/

DESIGN:

Electronic databases will be systematically searched for publications that report the association between dialysis modality (HD or PD) with death from any cause and cause-specific death in incident patients with end-stage kidney disease. The database searches will be supplemented by searching through citations and references and consultation with experts. Studies published before 1995 will be excluded. Screening of both titles and abstracts will be done by two independent reviewers. All disagreements will be resolved by an independent third reviewer. A quantitative meta-analysis of effect sizes and standard errors will be applied.

DISCUSSION:

Our systematic review will update previous evidence summaries and provide a quantitative and standardized assessment of the contemporary literature comparing HD and PD including published and unpublished non-English studies from greater China, Taiwan, and Japan. This review will inform shared decision-making around initial dialysis modality choice and jurisdiction-level considerations of dialysis practice. SYSTEMATIC REVIEW REGISTRATION PROSPERO CRD42018111829.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Causas de Morte / Diálise Renal / Falência Renal Crônica Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Causas de Morte / Diálise Renal / Falência Renal Crônica Idioma: En Ano de publicação: 2019 Tipo de documento: Article