Targeting Water in the Brain: Role of Aquaporin-4 in Ischemic Brain Edema.

Mamtilahun, Muyassar; Tang, Guanghui; Zhang, Zhijun; Wang, Yongting; Tang, Yaohui; Yang, Guo-Yuan

Mamtilahun, Muyassar; Tang, Guanghui; Zhang, Zhijun; Wang, Yongting; Tang, Yaohui; Yang, Guo-Yuan.

Afiliação

Mamtilahun M; Neuroscience and Neuroengineering Research Center, Med-X Research Institute, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China.
Tang G; Institute of Molecular Health Sciences, ETH Zurich, 8093 Zurich, Switzerland.
Zhang Z; Neuroscience and Neuroengineering Research Center, Med-X Research Institute, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China.
Wang Y; Neuroscience and Neuroengineering Research Center, Med-X Research Institute, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China.
Tang Y; Neuroscience and Neuroengineering Research Center, Med-X Research Institute, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China.
Yang GY; Neuroscience and Neuroengineering Research Center, Med-X Research Institute, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China.

Curr Drug Targets ; 20(7): 748-755, 2019.

Article em En | MEDLINE | ID: mdl-30791865

Assuntos

Aquaporina 4/metabolismo; Edema Encefálico/metabolismo; Sistema Nervoso Central/metabolismo; Edema Encefálico/tratamento farmacológico; Regulação da Expressão Gênica; Humanos; Terapia de Alvo Molecular; Água/metabolismo

Palavras-chave

Aquaporin-4; brain edema; central nervous system; stroke; therapeutic target; water channel.

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Edema Encefálico / Sistema Nervoso Central / Aquaporina 4 Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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