Association of HTRA1 and ARMS2 gene polymorphisms with response to intravitreal ranibizumab among neovascular age-related macular degenerative subjects.

Mohamad, Nur Afiqah; Ramachandran, Vasudevan; Mohd Isa, Hazlita; Chan, Yoke Mun; Ngah, Nor Fariza; Ching, Siew Mooi; Hoo, Fan Kee; Wan Sulaiman, Wan Aliaa; Inche Mat, Liyana Najwa; Mohamed, Mohd Hazmi

Mohamad, Nur Afiqah; Ramachandran, Vasudevan; Mohd Isa, Hazlita; Chan, Yoke Mun; Ngah, Nor Fariza; Ching, Siew Mooi; Hoo, Fan Kee; Wan Sulaiman, Wan Aliaa; Inche Mat, Liyana Najwa; Mohamed, Mohd Hazmi.

Afiliação

Mohamad NA; Malaysian Research Institute on Ageing, Universiti Putra Malaysia, 43400, Serdang, Selangor DE, Malaysia.
Ramachandran V; Malaysian Research Institute on Ageing, Universiti Putra Malaysia, 43400, Serdang, Selangor DE, Malaysia. vasudevan@upm.edu.my.
Mohd Isa H; Department of Ophthalmology, Universiti Kebangsaan Malaysia Medical Centre, 56000, Cheras, Kuala Lumpur, Malaysia.
Chan YM; Malaysian Research Institute on Ageing, Universiti Putra Malaysia, 43400, Serdang, Selangor DE, Malaysia.
Ngah NF; Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor DE, Malaysia.
Ching SM; Department of Ophthalmology, Hospital Selayang, Lebuhraya Selayang-Kepong, 68100, Batu Caves, Malaysia.
Hoo FK; Department of Family Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor DE, Malaysia.
Wan Sulaiman WA; Department of Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor DE, Malaysia.
Inche Mat LN; Department of Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor DE, Malaysia.
Mohamed MH; Department of Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor DE, Malaysia.

Hum Genomics ; 13(1): 13, 2019 02 22.

Article em En | MEDLINE | ID: mdl-30795802

Assuntos

Serina Peptidase 1 de Requerimento de Alta Temperatura A/genética; Degeneração Macular/tratamento farmacológico; Degeneração Macular/genética; Proteínas/genética; Ranibizumab/uso terapêutico; Idoso; Inibidores da Angiogênese/uso terapêutico; Feminino; Expressão Gênica/efeitos dos fármacos; Homozigoto; Humanos; Masculino; Pessoa de Meia-Idade; Polimorfismo de Nucleotídeo Único; Estudos Prospectivos; Resultado do Tratamento

Palavras-chave

Age-related macular degeneration; Age-related maculopathy susceptibility 2; High temperature requirement a serine peptidase 1; Polymorphism; Ranibizumab

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas / Ranibizumab / Serina Peptidase 1 de Requerimento de Alta Temperatura A / Degeneração Macular Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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