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Attenuation of doxorubicin-induced cardiotoxicity in a human in vitro cardiac model by the induction of the NRF-2 pathway.
Tomlinson, Lauren; Lu, Zhen Qi; Bentley, Robert A; Colley, Helen E; Murdoch, Craig; Webb, Steven D; Cross, Michael J; Copple, Ian M; Sharma, Parveen.
Afiliação
  • Tomlinson L; MRC Centre for Drug Safety Science, Department of Clinical and Molecular Pharmacology, University of Liverpool, Liverpool, UK.
  • Lu ZQ; School of Medicine, University of Queensland, St. Lucia, Queensland, 4006, Australia.
  • Bentley RA; MRC Centre for Drug Safety Science, Department of Clinical and Molecular Pharmacology, University of Liverpool, Liverpool, UK.
  • Colley HE; School of Clinical Dentistry, University of Sheffield, Sheffield, S10 2TA, UK.
  • Murdoch C; School of Clinical Dentistry, University of Sheffield, Sheffield, S10 2TA, UK.
  • Webb SD; Department of Applied Mathematics, Liverpool John Moores University, Liverpool, L3 3AF, UK; EPSRC Liverpool Centre for Mathematics in Healthcare, Department of Mathematical Sciences, University of Liverpool, Liverpool L69 7ZL, UK.
  • Cross MJ; MRC Centre for Drug Safety Science, Department of Clinical and Molecular Pharmacology, University of Liverpool, Liverpool, UK.
  • Copple IM; MRC Centre for Drug Safety Science, Department of Clinical and Molecular Pharmacology, University of Liverpool, Liverpool, UK.
  • Sharma P; MRC Centre for Drug Safety Science, Department of Clinical and Molecular Pharmacology, University of Liverpool, Liverpool, UK. Electronic address: Parveen.Sharma@liverpool.ac.uk.
Biomed Pharmacother ; 112: 108637, 2019 Apr.
Article em En | MEDLINE | ID: mdl-30798127
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doxorrubicina / Esferoides Celulares / Fator 2 Relacionado a NF-E2 / Coração / Antibióticos Antineoplásicos Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doxorrubicina / Esferoides Celulares / Fator 2 Relacionado a NF-E2 / Coração / Antibióticos Antineoplásicos Idioma: En Ano de publicação: 2019 Tipo de documento: Article