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Double deletion of PINK1 and Parkin impairs hepatic mitophagy and exacerbates acetaminophen-induced liver injury in mice.
Wang, Hua; Ni, Hong-Min; Chao, Xiaojuan; Ma, Xiaowen; Rodriguez, Yssa Ann; Chavan, Hemantkumar; Wang, Shaogui; Krishnamurthy, Partha; Dobrowsky, Rick; Xu, De-Xiang; Jaeschke, Hartmut; Ding, Wen-Xing.
Afiliação
  • Wang H; Department of Toxicology, School of Public Health, Anhui Medical University, Hefei City, Anhui Province, 230032, China; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS, 66160, USA.
  • Ni HM; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS, 66160, USA.
  • Chao X; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS, 66160, USA.
  • Ma X; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS, 66160, USA.
  • Rodriguez YA; Department of Pharmacology and Toxicology, University of Kansas, Lawrence, KS, 66045, USA.
  • Chavan H; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS, 66160, USA.
  • Wang S; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS, 66160, USA.
  • Krishnamurthy P; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS, 66160, USA.
  • Dobrowsky R; Department of Pharmacology and Toxicology, University of Kansas, Lawrence, KS, 66045, USA.
  • Xu DX; Department of Toxicology, School of Public Health, Anhui Medical University, Hefei City, Anhui Province, 230032, China.
  • Jaeschke H; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS, 66160, USA.
  • Ding WX; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS, 66160, USA. Electronic address: wxding@kumc.edu.
Redox Biol ; 22: 101148, 2019 04.
Article em En | MEDLINE | ID: mdl-30818124
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Deleção de Genes / Hepatócitos / Ubiquitina-Proteína Ligases / Doença Hepática Induzida por Substâncias e Drogas / Mitofagia Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Deleção de Genes / Hepatócitos / Ubiquitina-Proteína Ligases / Doença Hepática Induzida por Substâncias e Drogas / Mitofagia Idioma: En Ano de publicação: 2019 Tipo de documento: Article