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RNA exploits an exposed regulatory site to inhibit the enzymatic activity of PRC2.
Zhang, Qi; McKenzie, Nicholas J; Warneford-Thomson, Robert; Gail, Emma H; Flanigan, Sarena F; Owen, Brady M; Lauman, Richard; Levina, Vitalina; Garcia, Benjamin A; Schittenhelm, Ralf B; Bonasio, Roberto; Davidovich, Chen.
Afiliação
  • Zhang Q; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia.
  • McKenzie NJ; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia.
  • Warneford-Thomson R; Epigenetics Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Gail EH; Graduate Group in Biochemistry and Biophysics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Flanigan SF; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia.
  • Owen BM; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia.
  • Lauman R; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia.
  • Levina V; Epigenetics Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Garcia BA; Graduate Group in Biochemistry and Biophysics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Schittenhelm RB; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia.
  • Bonasio R; Epigenetics Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Davidovich C; Department of Biochemistry and Biophysics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Nat Struct Mol Biol ; 26(3): 237-247, 2019 03.
Article em En | MEDLINE | ID: mdl-30833789
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA / Histonas / Proteínas de Ligação a RNA / Complexo Repressor Polycomb 2 Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA / Histonas / Proteínas de Ligação a RNA / Complexo Repressor Polycomb 2 Idioma: En Ano de publicação: 2019 Tipo de documento: Article