Loss of human arylamine N-acetyltransferase I regulates mitochondrial function by inhibition of the pyruvate dehydrogenase complex.

Wang, Lili; Minchin, Rodney F; Essebier, Patricia J; Butcher, Neville J

Wang, Lili; Minchin, Rodney F; Essebier, Patricia J; Butcher, Neville J.

Afiliação

Wang L; Molecular and Cellular Pharmacology Laboratory, School of Biomedical Sciences, The University of Queensland, St Lucia, Brisbane, 4072 Australia.
Minchin RF; Molecular and Cellular Pharmacology Laboratory, School of Biomedical Sciences, The University of Queensland, St Lucia, Brisbane, 4072 Australia. Electronic address: r.minchin@uq.edu.au.
Essebier PJ; Molecular and Cellular Pharmacology Laboratory, School of Biomedical Sciences, The University of Queensland, St Lucia, Brisbane, 4072 Australia.
Butcher NJ; Molecular and Cellular Pharmacology Laboratory, School of Biomedical Sciences, The University of Queensland, St Lucia, Brisbane, 4072 Australia.

Int J Biochem Cell Biol ; 110: 84-90, 2019 05.

Article em En | MEDLINE | ID: mdl-30836144

Assuntos

Arilamina N-Acetiltransferase/deficiência; Arilamina N-Acetiltransferase/genética; Deleção de Genes; Isoenzimas/deficiência; Isoenzimas/genética; Mitocôndrias/metabolismo; Complexo Piruvato Desidrogenase/metabolismo; Transporte Biológico/genética; Regulação Neoplásica da Expressão Gênica; Glucose/metabolismo; Células HT29; Humanos; Complexo Piruvato Desidrogenase/antagonistas & inibidores

Palavras-chave

Arylamine N-acetyltransferase; Mitochondria; Pyruvate dehydrogenase

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Arilamina N-Acetiltransferase / Complexo Piruvato Desidrogenase / Deleção de Genes / Isoenzimas / Mitocôndrias Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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