Enantioselective recognition of sutezolid by cyclodextrin modified non-aqueous capillary electrophoresis and explanation of complex formation by means of infrared spectroscopy, NMR and molecular modelling.

Michalska, Katarzyna; Bocian, Wojciech; Bednarek, Elzbieta; Palys, Barbara; Cielecka-Piontek, Judyta

Michalska, Katarzyna; Bocian, Wojciech; Bednarek, Elzbieta; Palys, Barbara; Cielecka-Piontek, Judyta.

Afiliação

Michalska K; Department of Antibiotics and Microbiology, National Medicines Institute, Chelmska 30/34, 00-725, Warsaw, Poland. Electronic address: k.michalska@nil.gov.pl.
Bocian W; Department of Counterfeit Medicinal Products and Drugs, National Medicines Institute, Chelmska 30/34, 00-725, Warsaw, Poland.
Bednarek E; Department of Counterfeit Medicinal Products and Drugs, National Medicines Institute, Chelmska 30/34, 00-725, Warsaw, Poland.
Palys B; Laboratory of Electrochemistry, Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093, Warsaw, Poland.
Cielecka-Piontek J; Department of Pharmacognosy, Poznan University of Medical Sciences, Swiecickiego 4, 60-781, Poznan, Poland.

J Pharm Biomed Anal ; 169: 49-59, 2019 May 30.

Article em En | MEDLINE | ID: mdl-30836246

Assuntos

Ciclodextrinas/química; Oxazolidinonas/química; Eletroforese Capilar/métodos; Linezolida/química; Espectroscopia de Ressonância Magnética/métodos; Modelos Moleculares; Espectrofotometria Infravermelho/métodos; Estereoisomerismo; Tetrazóis/química; beta-Ciclodextrinas/química

Palavras-chave

CD-NACE; Enantioseparation; Molecular modelling; Spectroscopic approach; Sutezolid

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ciclodextrinas / Oxazolidinonas Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ciclodextrinas / Oxazolidinonas Idioma: En Ano de publicação: 2019 Tipo de documento: Article