Identification and functional analyses of disease-associated P4-ATPase phospholipid flippase variants in red blood cells.

Liou, Angela Y; Molday, Laurie L; Wang, Jiao; Andersen, Jens Peter; Molday, Robert S

Liou, Angela Y; Molday, Laurie L; Wang, Jiao; Andersen, Jens Peter; Molday, Robert S.

Afiliação

Liou AY; From the Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada and.
Molday LL; From the Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada and.
Wang J; From the Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada and.
Andersen JP; Department of Biomedicine, Aarhus University, Ole Worms Allé 4, Building 1160, DK-8000 Aarhus C, Denmark.
Molday RS; From the Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada and molday@mail.ubc.ca.

J Biol Chem ; 294(17): 6809-6821, 2019 04 26.

Article em En | MEDLINE | ID: mdl-30850395

Assuntos

Adenosina Trifosfatases/metabolismo; Eritrócitos/enzimologia; Fosfolipídeos/metabolismo; Adenosina Trifosfatases/genética; Animais; Membrana Eritrocítica/enzimologia; Membrana Eritrocítica/metabolismo; Humanos; Proteínas de Membrana/metabolismo; Camundongos; Proteínas de Transferência de Fosfolipídeos/metabolismo; Fosforilação; Dobramento de Proteína

Palavras-chave

ATP11C; ATPase; CDC50A; P4-ATPases; cell biology; disease mechanisms; erythrocyte; lipid flippases; lipid transport; phosphatidylserine

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfolipídeos / Adenosina Trifosfatases / Eritrócitos Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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