Cluster-Transition Determining Sites Underlying the Antigenic Evolution of Seasonal Influenza Viruses.

Quan, Lijun; Ji, Chengyang; Ding, Xiao; Peng, Yousong; Liu, Mi; Sun, Jiya; Jiang, Taijiao; Wu, Aiping

Quan, Lijun; Ji, Chengyang; Ding, Xiao; Peng, Yousong; Liu, Mi; Sun, Jiya; Jiang, Taijiao; Wu, Aiping.

Afiliação

Quan L; Center for Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Suzhou Institute of Systems Medicine, Suzhou, China.
Ji C; School of Computer Science and Technology, Soochow University, Suzhou, China.
Ding X; Center for Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Suzhou Institute of Systems Medicine, Suzhou, China.
Peng Y; Center for Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Suzhou Institute of Systems Medicine, Suzhou, China.
Liu M; College of Biology, Human University, Changsha, China.
Sun J; Jiangsu Institute of Clinical Immunology & Jiangsu Key Laboratory of Clinical Immunology, First Affiliated Hospital of Soochow University, Suzhou, China.
Jiang T; Center for Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Suzhou Institute of Systems Medicine, Suzhou, China.
Wu A; Center for Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Suzhou Institute of Systems Medicine, Suzhou, China.

Mol Biol Evol ; 36(6): 1172-1186, 2019 06 01.

Article em En | MEDLINE | ID: mdl-30851115

Assuntos

Antígenos Virais/genética; Evolução Molecular; Hemaglutininas/genética; Vírus da Influenza A Subtipo H1N1/genética; Vírus da Influenza A Subtipo H3N2/genética; Algoritmos; Técnicas Genéticas; Vírus da Influenza A Subtipo H1N1/imunologia; Vírus da Influenza A Subtipo H3N2/imunologia; Software

Palavras-chave

antigenic evolution; cluster-transition determining sites; gradient boosting classifier; hemagglutinin protein; seasonal influenza viruses

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Evolução Molecular / Vírus da Influenza A Subtipo H1N1 / Vírus da Influenza A Subtipo H3N2 / Hemaglutininas / Antígenos Virais Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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