A randomized clinical trial to evaluate home-based assessment of people over 75 years old.
Alzheimers Dement
; 15(5): 615-624, 2019 05.
Article
em En
| MEDLINE
| ID: mdl-30872114
INTRODUCTION: There is an unmet need for effective methods for conducting dementia prevention trials. METHODS: Home-based assessment study compared feasibility and efficiency, ability to capture change over time using in-home instruments, and ability to predict cognitive conversion using predefined triggers in a randomized clinical trial in (1) mail-in questionnaire/live telephone interviews, (2) automated telephone/interactive voice recognition, and (3) internet-based computer Kiosk technologies. Primary endpoint was defined as cognitive conversion. RESULTS: Analysis followed a modified intent-to-treat principle. Dropout rates were low and similar across technologies but participants in Kiosk were more likely to dropout earlier. Staff resources needed were higher in Kiosk. In-home instruments distinguished conversion and stable groups. Cognitively stable group showed improvement in cognitive measures. Triggering was associated with higher likelihood of conversion but statistically significant only in mail-in questionnaire/live telephone interviews. DISCUSSION: Relatively low efficiency of internet-based assessment compared with testing by live-assessors has implications for internet-based recruitment and assessment efforts currently proposed for diverse populations.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Avaliação Geriátrica
/
Inquéritos e Questionários
/
Demência
/
Voluntários Saudáveis
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article