Your browser doesn't support javascript.
loading
A randomized clinical trial to evaluate home-based assessment of people over 75 years old.
Sano, Mary; Zhu, Carolyn W; Kaye, Jeffrey; Mundt, James C; Hayes, Tamara L; Ferris, Steven; Thomas, Ronald G; Sun, Chung-Kai; Jiang, Yanxin; Donohue, Michael C; Schneider, Lon S; Egelko, Susan; Aisen, Paul S; Feldman, Howard H.
Afiliação
  • Sano M; Department of Psychiatry, Alzheimer Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA; James J Peters VAMC, Bronx, NY, USA. Electronic address: mary.sano@mssm.edu.
  • Zhu CW; Department of Psychiatry, Alzheimer Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA; James J Peters VAMC, Bronx, NY, USA; Brookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Kaye J; Department of Neurology and Biomedical Engineering, Oregon Health & Science University, Portland, OR, USA.
  • Mundt JC; Wisconsin Department of Health Services, Division of Care and Treatment Services, Mauston, WI, USA.
  • Hayes TL; Oregon Center for Aging and Technology, Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR, USA.
  • Ferris S; Center for Cognitive Neurology, New York University Langone Medical Center, New York, NY, USA.
  • Thomas RG; Department of Neurosciences, San Diego, CA, USA; Department of Family and Preventive Medicine, University of California, San Diego, CA, USA.
  • Sun CK; Alzheimer's Therapeutic Research Institute, Keck School of Medicine, University of Southern California, San Diego, CA, USA.
  • Jiang Y; Alzheimer's Therapeutic Research Institute, Keck School of Medicine, University of Southern California, San Diego, CA, USA.
  • Donohue MC; Alzheimer's Therapeutic Research Institute, Keck School of Medicine, University of Southern California, San Diego, CA, USA.
  • Schneider LS; Department of Psychiatry and the Behavioral Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Egelko S; Department of Psychiatry, Alzheimer Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Aisen PS; Alzheimer's Therapeutic Research Institute, Keck School of Medicine, University of Southern California, San Diego, CA, USA.
  • Feldman HH; Department of Neurosciences, University of California, San Diego, CA, USA.
Alzheimers Dement ; 15(5): 615-624, 2019 05.
Article em En | MEDLINE | ID: mdl-30872114
INTRODUCTION: There is an unmet need for effective methods for conducting dementia prevention trials. METHODS: Home-based assessment study compared feasibility and efficiency, ability to capture change over time using in-home instruments, and ability to predict cognitive conversion using predefined triggers in a randomized clinical trial in (1) mail-in questionnaire/live telephone interviews, (2) automated telephone/interactive voice recognition, and (3) internet-based computer Kiosk technologies. Primary endpoint was defined as cognitive conversion. RESULTS: Analysis followed a modified intent-to-treat principle. Dropout rates were low and similar across technologies but participants in Kiosk were more likely to dropout earlier. Staff resources needed were higher in Kiosk. In-home instruments distinguished conversion and stable groups. Cognitively stable group showed improvement in cognitive measures. Triggering was associated with higher likelihood of conversion but statistically significant only in mail-in questionnaire/live telephone interviews. DISCUSSION: Relatively low efficiency of internet-based assessment compared with testing by live-assessors has implications for internet-based recruitment and assessment efforts currently proposed for diverse populations.
Assuntos
Palavras-chave

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Avaliação Geriátrica / Inquéritos e Questionários / Demência / Voluntários Saudáveis Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Avaliação Geriátrica / Inquéritos e Questionários / Demência / Voluntários Saudáveis Idioma: En Ano de publicação: 2019 Tipo de documento: Article