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Exploring isoxazoles and pyrrolidinones decorated with the 4,6-dimethoxy-1,3,5-triazine unit as human farnesyltransferase inhibitors.
Lucescu, Liliana; Ghinet, Alina; Shova, Sergiu; Magnez, Romain; Thuru, Xavier; Farce, Amaury; Rigo, Benoît; Belei, Dalila; Dubois, Joëlle; Bîcu, Elena.
Afiliação
  • Lucescu L; Faculty of Chemistry, Al. I. Cuza' University of Iasi, Iasi, Romania.
  • Ghinet A; Faculty of Chemistry, Al. I. Cuza' University of Iasi, Iasi, Romania.
  • Shova S; Inserm U995, LIRIC, Faculté de médecine-Pôle recherche, Université de Lille, CHRU de Lille, Lille, France.
  • Magnez R; Laboratoire de Chimie Durable et Santé, Hautes Etudes d'Ingénieur (HEI), Yncréa Hauts-de-France, UC Lille, Lille, France.
  • Thuru X; Petru Poni' Institute of Macromolecular Chemistry, Iasi, Romania.
  • Farce A; Univ. Lille, UMR-S 1172 - JPARC - Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer, Lille, France.
  • Rigo B; Univ. Lille, UMR-S 1172 - JPARC - Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer, Lille, France.
  • Belei D; Inserm U995, LIRIC, Faculté de médecine-Pôle recherche, Université de Lille, CHRU de Lille, Lille, France.
  • Dubois J; Faculté des Sciences Pharmaceutiques et Biologiques de Lille, Lille, France.
  • Bîcu E; Inserm U995, LIRIC, Faculté de médecine-Pôle recherche, Université de Lille, CHRU de Lille, Lille, France.
Arch Pharm (Weinheim) ; 352(5): e1800227, 2019 May.
Article em En | MEDLINE | ID: mdl-30947375
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirrolidinonas / Triazinas / Inibidores Enzimáticos / Farnesiltranstransferase / Isoxazóis Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirrolidinonas / Triazinas / Inibidores Enzimáticos / Farnesiltranstransferase / Isoxazóis Idioma: En Ano de publicação: 2019 Tipo de documento: Article